Single cell transcriptomics: Methods and applications

Itamar Kanter, Tomer Kalisky

פרסום מחקרי: פרסום בכתב עתסקירהביקורת עמיתים

תקציר

Traditionally, gene expression measurements were performed on "bulk" samples containing populations of thousands of cells. Recent advances in genomic technology have made it possible to measure gene expression in hundreds of individual cells at a time. As a result, cellular properties that were previously masked in "bulk" measurements can now be observed directly. In this review we will survey emerging technologies for single cell transcriptomics, and describe how they are used to study complex disease such as cancer, as well as other biological phenomena such as tissue regeneration, embryonic development, and immune response.

שפה מקוריתאנגלית
מספר המאמר53
כתב עתFrontiers in Oncology
כרך5
מספר גיליוןFEB
מזהי עצם דיגיטלי (DOIs)
סטטוס פרסוםפורסם - 2015

ASJC Scopus subject areas

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