Mesenchymal stem cells for in vitro modeling and cell-based therapy of human diseases and banks thereof

Chaya Brodie (ממציא), Shimon Slavin (ממציא)

פרסום מחקרי: פטנט

תקציר

A method of qualifying a mesenchymal stem cell (MSC) population is disclosed. The method comprises:
(a) ex vivo differentiating a population of mesenchymal stem cells originating from the subject towards a first lineage-specific cell, the first lineage-specific cell being associated with a brain disease;
(b) ex vivo differentiating a population of mesenchymal stem cells originating from a healthy subject towards the first lineage-specific cell;
(c) comparing an effect of the first lineage specific cell derived from the subject with an effect of the first lineage specific cell derived from the healthy subject on a second lineage specific cell associated with the brain disease, wherein a difference in the effect above or below a predetermined level is indicative of a qualification of a mesenchymal stem cell population for cell therapy of said brain disease.
שפה מקוריתאנגלית
מספר פטנטUS20150024966A1
סטטוס פרסוםפורסם - 22 ינו׳ 2015

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