Monitoring of drug delivery is an essential technique for innovative medical treatments, including cancer therapy. Fluorescence imaging has become an important tool in tracking drug delivery and thus improving treatment efficacy. Binding fluorescent reporters to therapeutic agents paves the way to real time monitoring of drug delivery and drug distribution in vitro and in vivo. This review discusses fluorescent reporters used in drug delivery monitoring and provides an overview of recent achievements in the development of fluorescence based drug delivery systems.
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