Ecological dynamics of the vaginal microbiome in relation to health and disease

Shirley Greenbaum, Gili Greenbaum, Jacob Moran-Gilad, Adi Y. Weintruab

פרסום מחקרי: פרסום בכתב עתסקירהביקורת עמיתים

תקציר

The bacterial composition of the vaginal microbiome is thought to be related to health and disease states of women. This microbiome is particularly dynamic, with compositional changes related to pregnancy, menstruation, and disease states such as bacterial vaginosis. In order to understand these dynamics and their impact on health and disease, ecological theories have been introduced to study the complex interactions between the many taxa in the vaginal bacterial ecosystem. The goal of this review is to introduce the ecological principles that are used in the study of the vaginal microbiome and its dynamics, and to review the application of ecology to vaginal microbial communities with respect to health and disease. Although applications of vaginal microbiome analysis and modulation have not yet been introduced into the routine clinical setting, a deeper understanding of its dynamics has the potential to facilitate development of future practices, for example in the context of postmenopausal vaginal symptoms, stratifying risk for obstetric complications, and controlling sexually transmitted infections.

שפה מקוריתאנגלית אמריקאית
עמודים (מ-עד)324-335
מספר עמודים12
כתב עתAmerican Journal of Obstetrics and Gynecology
כרך220
מספר גיליון4
מזהי עצם דיגיטלי (DOIs)
סטטוס פרסוםפורסם - 1 אפר׳ 2019

ASJC Scopus subject areas

  • ???subjectarea.asjc.2700.2729???

טביעת אצבע

להלן מוצגים תחומי המחקר של הפרסום 'Ecological dynamics of the vaginal microbiome in relation to health and disease'. יחד הם יוצרים טביעת אצבע ייחודית.

פורמט ציטוט ביבליוגרפי