Color flow mapping: A non-invasive tool for characterizing and differentiating between uveal melanomas and choroidal metastases

Meira Neudorfer, Michael Waisbourd, Irene Anteby, Alon Liran, Dafna Goldenberg, Adiel Barak, Ada Kessler

פרסום מחקרי: פרסום בכתב עתמאמרביקורת עמיתים

תקציר

The objective of this study was to characterize and differentiate vascular patterns of choroidal melanomas and choroidal metastases by color flow mapping (CFM). We conducted a retrospective chart study on CFM findings in 18 patients with choroidal melanomas and 10 patients with choroidal metastases. We evaluated the possibilities of applying CFM to identify hypo-versus hyper-vascularity within the tumor, a central 'dominant vessel', and Doppler signals in the tumor's center and/or periphery. CFM demonstrated hypervascular patterns in 33% melanomas and 100% metastases (p<0.0001). CFM identified a central dominant vessel in 94% melanomas and 0/10 metastases (p<0.0001). Vascularity occupied the center of 11/18 melanomas and 0/10 metastases (p<0.0001), the periphery of 2/18 melanomas and 9/10 metastases (p<0.0001), and equally occupied the tumor's center and periphery of 5/18 melanomas and 1/10 metastases (p<0.0001). Based on our findings, we conclude that CFM was capable of non-invasively demonstrating different and distinct vascular patterns in malignant choroidal melanomas and choroidal metastases.

שפה מקוריתאנגלית
עמודים (מ-עד)91-96
מספר עמודים6
כתב עתOncology Reports
כרך25
מספר גיליון1
מזהי עצם דיגיטלי (DOIs)
סטטוס פרסוםפורסם - ינו׳ 2011

ASJC Scopus subject areas

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