Age of onset in obsessive-compulsive disorder: Admixture analysis with a large sample

G. E. Anholt, I. M. Aderka, A. J.L.M. Van Balkom, J. H. Smit, K. Schruers, N. J.A. Van Der Wee, M. Eikelenboom, V. De Luca, P. Van Oppen

פרסום מחקרי: פרסום בכתב עתמאמרביקורת עמיתים

תקציר

Background Research into age of onset in obsessive-compulsive disorder (OCD) has indicated significant differences between patients with early and late onset of the disorder. However, multiple criteria have been used arbitrarily for differentiating between early-and late-onset OCD, rendering inconsistent results that are difficult to interpret. Method In the current study, admixture analysis was conducted in a sample of 377 OC patients to determine the number of underlying populations of age of onset and associated demographic and clinical characteristics. Various measures of anxiety, depression, co-morbidity, autism, OCD, tics and attention deficit hyperactivity disorder (ADHD) symptoms were administered. Results A bimodal age of onset was established and the best-fitting cut-off score between early and late age of onset was 20 years (early age of onset â

שפה מקוריתאנגלית אמריקאית
עמודים (מ-עד)185-194
מספר עמודים10
כתב עתPsychological Medicine
כרך44
מספר גיליון1
מזהי עצם דיגיטלי (DOIs)
סטטוס פרסוםפורסם - 1 ינו׳ 2014

ASJC Scopus subject areas

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טביעת אצבע

להלן מוצגים תחומי המחקר של הפרסום 'Age of onset in obsessive-compulsive disorder: Admixture analysis with a large sample'. יחד הם יוצרים טביעת אצבע ייחודית.

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