Water in N-Heterocyclic Carbene-Assisted Catalysis

Efrat Levin, Elisa Ivry, Charles E. Diesendruck, N. Gabriel Lemcoff

Research output: Contribution to journalReview articlepeer-review


Palladium has a very rich organometallic repertoire, and its high functional group tolerance makes it an attractive metal to study catalysis in water. Several arylboronic acids and aryl iodides or bromides were investigated, including substrates with electron-donating and electron-withdrawing groups. A control reaction with sodium hydroxide and methanol gave comparable results, supporting this theory; unfortunately other organic bases, such as sodium ethoxide or potassium tert-butoxide, were not tested to support this theory. Increased complex solubility in water may be achieved by attaching charged groups to the NHC ligand.

Original languageEnglish
Pages (from-to)4607-4692
Number of pages86
JournalChemical Reviews
Issue number11
StatePublished - 10 Jun 2015

All Science Journal Classification (ASJC) codes

  • Chemistry(all)


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