Volume Conduction Coupling of Whisker-Evoked Cortical LFP in the Mouse Olfactory Bulb

Ana Parabucki; Ilan Lampl

doi:https://doi.org/10.1016/j.celrep.2017.09.094

Volume Conduction Coupling of Whisker-Evoked Cortical LFP in the Mouse Olfactory Bulb

Ana Parabucki, Ilan Lampl

Department of Brain Sciences

Weizmann Institute of Science

Research output: Contribution to journal › Article › peer-review

Abstract

Local field potentials (LFPs) are an important measure of brain activity and have been used to address various mechanistic and behavioral questions. We revealed a prominent whisker-evoked LFP signal in the olfactory bulb and investigated its physiology. This signal, dependent on barrel cortex activation and highly correlated with its local activity, represented a pure volume conduction signal that was sourced back to the activity in the ventro-lateral orbitofrontal cortex, located a few millimeters away. Thus, we suggest that special care should be taken when acquiring and interpreting LFP data.

Original language	English
Pages (from-to)	919-925
Number of pages	7
Journal	Cell Reports
Volume	21
Issue number	4
DOIs	https://doi.org/10.1016/j.celrep.2017.09.094 https://doi.org/10.1016/j.celrep.2017.09.094
State	Published - 24 Oct 2017

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@article{2c3320a8c0274dcea13e8678fcf4d24e,

title = "Volume Conduction Coupling of Whisker-Evoked Cortical LFP in the Mouse Olfactory Bulb",

abstract = "Local field potentials (LFPs) are an important measure of brain activity and have been used to address various mechanistic and behavioral questions. We revealed a prominent whisker-evoked LFP signal in the olfactory bulb and investigated its physiology. This signal, dependent on barrel cortex activation and highly correlated with its local activity, represented a pure volume conduction signal that was sourced back to the activity in the ventro-lateral orbitofrontal cortex, located a few millimeters away. Thus, we suggest that special care should be taken when acquiring and interpreting LFP data.",

author = "Ana Parabucki and Ilan Lampl",

note = "DFG-SFB [1089]; DeCipher ERA-NET NEURON [01EW1606]; Human Frontiers Science Program [RGP0044/2015]",

year = "2017",

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doi = "https://doi.org/10.1016/j.celrep.2017.09.094",

language = "الإنجليزيّة",

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T1 - Volume Conduction Coupling of Whisker-Evoked Cortical LFP in the Mouse Olfactory Bulb

AU - Parabucki, Ana

AU - Lampl, Ilan

N1 - DFG-SFB [1089]; DeCipher ERA-NET NEURON [01EW1606]; Human Frontiers Science Program [RGP0044/2015]

PY - 2017/10/24

Y1 - 2017/10/24

N2 - Local field potentials (LFPs) are an important measure of brain activity and have been used to address various mechanistic and behavioral questions. We revealed a prominent whisker-evoked LFP signal in the olfactory bulb and investigated its physiology. This signal, dependent on barrel cortex activation and highly correlated with its local activity, represented a pure volume conduction signal that was sourced back to the activity in the ventro-lateral orbitofrontal cortex, located a few millimeters away. Thus, we suggest that special care should be taken when acquiring and interpreting LFP data.

AB - Local field potentials (LFPs) are an important measure of brain activity and have been used to address various mechanistic and behavioral questions. We revealed a prominent whisker-evoked LFP signal in the olfactory bulb and investigated its physiology. This signal, dependent on barrel cortex activation and highly correlated with its local activity, represented a pure volume conduction signal that was sourced back to the activity in the ventro-lateral orbitofrontal cortex, located a few millimeters away. Thus, we suggest that special care should be taken when acquiring and interpreting LFP data.

U2 - https://doi.org/10.1016/j.celrep.2017.09.094

DO - https://doi.org/10.1016/j.celrep.2017.09.094

M3 - مقالة

SN - 2211-1247

VL - 21

SP - 919

EP - 925

JO - Cell Reports

JF - Cell Reports

IS - 4

ER -

Volume Conduction Coupling of Whisker-Evoked Cortical LFP in the Mouse Olfactory Bulb

Abstract

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