Using ChromEvol to Determine the Mode of Chromosomal Evolution

Marcial Escudero, Enrique Maguilla, José Ignacio Márquez-Corro, Santiago Martín-Bravo, Itay Mayrose, Anat Shafir, Lu Tan, Carrie Tribble, Rosana Zenil-Ferguson

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


The ChromEvol software was the first to implement a likelihood-based approach, using probabilistic models that depict the pattern of chromosome number change along a specified phylogeny. The initial models have been completed and expanded during the last years. New parameters that model polyploid chromosome evolution have been implemented in ChromEvol v.2. In recent years, new and more complex models have been developed. The BiChrom model is able to implement two distinct chromosome models for the two possible trait states of a binary character of interest. ChromoSSE jointly implements chromosome evolution, speciation, and extinction. In the near future, we will be able to study chromosome evolution with increasingly complex models.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
Number of pages19
StatePublished - 2023

Publication series

NameMethods in Molecular Biology


  • BiChrom
  • ChromEvol
  • ChromoPlus
  • ChromoSSE
  • Chromosome count
  • Dysploidy
  • Phylogeny
  • Polyploidy
  • Probabilistic model

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Genetics


Dive into the research topics of 'Using ChromEvol to Determine the Mode of Chromosomal Evolution'. Together they form a unique fingerprint.

Cite this