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Use of iPSC-derived brain organoids to study human brain evolution

Orly Reiner, Tamar Sapir, Arpan Parichha

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Recent advances in stem cell, genome editing, and iPSC technologies have made it possible to study human brain evolution using this iPSC-derived brain organoids as a model system.
In this chapter, we will explore the evolution of the human brain and the central nervous system and discuss what we can learn from genomic comparisons studies. We will also examine the model organisms used to study gene expression and cell biology and delve into the new world of iPSC-derived brain organoids and what this new model system can tell us about human brain evolution.
Original languageEnglish
Title of host publicationRecent Advances in iPSC Technology
PublisherElsevier
Pages157-177
Number of pages21
Volume5
ISBN (Electronic)9780128222317
ISBN (Print)9780128223260
DOIs
StatePublished - 2021

Publication series

NameAdvances in Stem Cell Biology
Volume5

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