US National Institutes of Health Prioritization of SARS-CoV-2 Variants

Sam Turner; Arghavan Alisoltani; Debbie Bratt; Liel Cohen-Lavi; Bethany L. Dearlove; Christian Drosten; Will M. Fischer; Ron A.M. Fouchier; Ana Silvia Gonzalez-Reiche; Lukasz Jaroszewski; Zain Khalil; Eric LeGresley; Marc Johnson; Terry C. Jones; Barbara Mühlemann; David O'Connor; Mayya Sedova; Maulik Shukla; James Theiler; Zachary S. Wallace; Hyejin Yoon; Yun Zhang; Harm van Bakel; Marciela M. Degrace; Elodie Ghedin; Adam Godzik; Tomer Hertz; Bette Korber; Jacob Lemieux; Anna M. Niewiadomska; Diane J. Post; Morgane Rolland; Richard Scheuermann; Derek J. Smith

doi:10.3201/eid2905.221646

US National Institutes of Health Prioritization of SARS-CoV-2 Variants

Sam Turner, Arghavan Alisoltani, Debbie Bratt, Liel Cohen-Lavi, Bethany L. Dearlove, Christian Drosten, Will M. Fischer, Ron A.M. Fouchier, Ana Silvia Gonzalez-Reiche, Lukasz Jaroszewski, Zain Khalil, Eric LeGresley, Marc Johnson, Terry C. Jones, Barbara Mühlemann, David O'Connor, Mayya Sedova, Maulik Shukla, James Theiler, Zachary S. WallaceHyejin Yoon, Yun Zhang, Harm van Bakel, Marciela M. Degrace, Elodie Ghedin, Adam Godzik, Tomer Hertz, Bette Korber, Jacob Lemieux, Anna M. Niewiadomska, Diane J. Post, Morgane Rolland, Richard Scheuermann, Derek J. Smith

The Shraga Segal Department of Microbiology and Immunology

Ben-Gurion University of the Negev

Research output: Contribution to journal › Article › peer-review

Abstract

Since late 2020, SARS-CoV-2 variants have regularly emerged with competitive and phenotypic differences from previously circulating strains, sometimes with the potential to escape from immunity produced by prior exposure and infection. The Early Detection group is one of the constituent groups of the US National Institutes of Health National Institute of Allergy and Infectious Diseases SARS-CoV-2 Assessment of Viral Evolution program. The group uses bioinformatic methods to monitor the emergence, spread, and potential phenotypic properties of emerging and circulating strains to identify the most relevant variants for experimental groups within the program to phenotypically characterize. Since April 2021, the group has prioritized variants monthly. Prioritization successes include rapidly identifying most major variants of SARS-CoV-2 and providing experimental groups within the National Institutes of Health program easy access to regularly updated information on the recent evolution and epidemiology of SARS-CoV-2 that can be used to guide phenotypic investigations.

Original language	American English
Pages (from-to)	E1-E9
Journal	Emerging Infectious Diseases
Volume	29
Issue number	5
DOIs	https://doi.org/10.3201/eid2905.221646
State	Published - 1 May 2023

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Epidemiology
Microbiology (medical)
Infectious Diseases

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10.3201/eid2905.221646

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Turner, S., Alisoltani, A., Bratt, D., Cohen-Lavi, L., Dearlove, B. L., Drosten, C., Fischer, W. M., Fouchier, R. A. M., Gonzalez-Reiche, A. S., Jaroszewski, L., Khalil, Z., LeGresley, E., Johnson, M., Jones, T. C., Mühlemann, B., O'Connor, D., Sedova, M., Shukla, M., Theiler, J., ... Smith, D. J. (2023). US National Institutes of Health Prioritization of SARS-CoV-2 Variants. Emerging Infectious Diseases, 29(5), E1-E9. https://doi.org/10.3201/eid2905.221646

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title = "US National Institutes of Health Prioritization of SARS-CoV-2 Variants",

abstract = "Since late 2020, SARS-CoV-2 variants have regularly emerged with competitive and phenotypic differences from previously circulating strains, sometimes with the potential to escape from immunity produced by prior exposure and infection. The Early Detection group is one of the constituent groups of the US National Institutes of Health National Institute of Allergy and Infectious Diseases SARS-CoV-2 Assessment of Viral Evolution program. The group uses bioinformatic methods to monitor the emergence, spread, and potential phenotypic properties of emerging and circulating strains to identify the most relevant variants for experimental groups within the program to phenotypically characterize. Since April 2021, the group has prioritized variants monthly. Prioritization successes include rapidly identifying most major variants of SARS-CoV-2 and providing experimental groups within the National Institutes of Health program easy access to regularly updated information on the recent evolution and epidemiology of SARS-CoV-2 that can be used to guide phenotypic investigations.",

author = "Sam Turner and Arghavan Alisoltani and Debbie Bratt and Liel Cohen-Lavi and Dearlove, {Bethany L.} and Christian Drosten and Fischer, {Will M.} and Fouchier, {Ron A.M.} and Gonzalez-Reiche, {Ana Silvia} and Lukasz Jaroszewski and Zain Khalil and Eric LeGresley and Marc Johnson and Jones, {Terry C.} and Barbara M{\"u}hlemann and David O'Connor and Mayya Sedova and Maulik Shukla and James Theiler and Wallace, {Zachary S.} and Hyejin Yoon and Yun Zhang and {van Bakel}, Harm and Degrace, {Marciela M.} and Elodie Ghedin and Adam Godzik and Tomer Hertz and Bette Korber and Jacob Lemieux and Niewiadomska, {Anna M.} and Post, {Diane J.} and Morgane Rolland and Richard Scheuermann and Smith, {Derek J.}",

year = "2023",

month = may,

day = "1",

doi = "10.3201/eid2905.221646",

language = "American English",

volume = "29",

pages = "E1--E9",

journal = "Emerging Infectious Diseases",

issn = "1080-6040",

publisher = "Centers for Disease Control and Prevention (CDC)",

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Turner, S, Alisoltani, A, Bratt, D, Cohen-Lavi, L, Dearlove, BL, Drosten, C, Fischer, WM, Fouchier, RAM, Gonzalez-Reiche, AS, Jaroszewski, L, Khalil, Z, LeGresley, E, Johnson, M, Jones, TC, Mühlemann, B, O'Connor, D, Sedova, M, Shukla, M, Theiler, J, Wallace, ZS, Yoon, H, Zhang, Y, van Bakel, H, Degrace, MM, Ghedin, E, Godzik, A, Hertz, T, Korber, B, Lemieux, J, Niewiadomska, AM, Post, DJ, Rolland, M, Scheuermann, R & Smith, DJ 2023, 'US National Institutes of Health Prioritization of SARS-CoV-2 Variants', Emerging Infectious Diseases, vol. 29, no. 5, pp. E1-E9. https://doi.org/10.3201/eid2905.221646

TY - JOUR

T1 - US National Institutes of Health Prioritization of SARS-CoV-2 Variants

AU - Turner, Sam

AU - Alisoltani, Arghavan

AU - Bratt, Debbie

AU - Cohen-Lavi, Liel

AU - Dearlove, Bethany L.

AU - Drosten, Christian

AU - Fischer, Will M.

AU - Fouchier, Ron A.M.

AU - Gonzalez-Reiche, Ana Silvia

AU - Jaroszewski, Lukasz

AU - Khalil, Zain

AU - LeGresley, Eric

AU - Johnson, Marc

AU - Jones, Terry C.

AU - Mühlemann, Barbara

AU - O'Connor, David

AU - Sedova, Mayya

AU - Shukla, Maulik

AU - Theiler, James

AU - Wallace, Zachary S.

AU - Yoon, Hyejin

AU - Zhang, Yun

AU - van Bakel, Harm

AU - Degrace, Marciela M.

AU - Ghedin, Elodie

AU - Godzik, Adam

AU - Hertz, Tomer

AU - Korber, Bette

AU - Lemieux, Jacob

AU - Niewiadomska, Anna M.

AU - Post, Diane J.

AU - Rolland, Morgane

AU - Scheuermann, Richard

AU - Smith, Derek J.

PY - 2023/5/1

Y1 - 2023/5/1

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AB - Since late 2020, SARS-CoV-2 variants have regularly emerged with competitive and phenotypic differences from previously circulating strains, sometimes with the potential to escape from immunity produced by prior exposure and infection. The Early Detection group is one of the constituent groups of the US National Institutes of Health National Institute of Allergy and Infectious Diseases SARS-CoV-2 Assessment of Viral Evolution program. The group uses bioinformatic methods to monitor the emergence, spread, and potential phenotypic properties of emerging and circulating strains to identify the most relevant variants for experimental groups within the program to phenotypically characterize. Since April 2021, the group has prioritized variants monthly. Prioritization successes include rapidly identifying most major variants of SARS-CoV-2 and providing experimental groups within the National Institutes of Health program easy access to regularly updated information on the recent evolution and epidemiology of SARS-CoV-2 that can be used to guide phenotypic investigations.

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DO - 10.3201/eid2905.221646

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SN - 1080-6040

VL - 29

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JO - Emerging Infectious Diseases

JF - Emerging Infectious Diseases

IS - 5

ER -

US National Institutes of Health Prioritization of SARS-CoV-2 Variants

Abstract

UN SDGs

All Science Journal Classification (ASJC) codes

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