@inbook{1567d8022768444d9a4d46b53b184056,
title = "Unraveling chemokine and chemokine receptor expression patterns using genetically engineered mice",
abstract = "Over the past 25 years, genetically engineered mouse models have become an integral and invaluable research tool to develop our understanding of mammalian physiology and pathology. This unit describes methods for generating transgenic mice, focusing on reporter animals relevant to chemokine receptor and ligand expression. Speci fi cally, we describe the use of bacterial arti fi cial chromosome (BAC) engineering and embryonic stem cell manipulation to generate {"} knock in {"} and transgenic mice.",
keywords = "Bacterial arti fi cial chromosome, Chemokines, Embryonic stem cells and mice",
author = "Simon Yona and Kim, {Ki Wook} and Rebecca Haffner and Steffen Jung",
note = "NA",
year = "2013",
month = apr,
day = "3",
doi = "10.1007/978-1-62703-426-5_8",
language = "الإنجليزيّة",
isbn = "9781627034258",
series = "Methods in Molecular Biology",
pages = "129--144",
booktitle = "Chemokines",
}