Treatment adherence and behavior of pediatric liver transplant recipients during the COVID-19 pandemic

Lev Dorfman, Raouf Nassar, Michal Rozenfeld Bar-Lev, Michal Shafir, Ilan Oseran, Yael Mozer-Glassberg, Rachel Gavish, Amit Assa, Raanan Shamir, Orith Waisbourd-Zinman

Research output: Contribution to journalArticlepeer-review


Background: The COVID-19 pandemic has affected medical care worldwide. Thus, we aimed to assess the impact of the COVID-19 pandemic on pediatric LT recipients. Methods: A cross-sectional study based on a structured internet or telephone survey was conducted among pediatric LT recipients. Survey results were compared with results of a survey conducted among pediatric patients with IBD. Results: Seventy-six pediatric LT patients participated in the study. Of them, 58 (76.3%) reported fear of severe COVID-19 infection due to LT or LT-associated medications. Half of the patients reported needing emotional support. Most patients (51, 67.1%) reported strictly following official guidance, while more stringent protective measures were taken by 64 (84.2%) patients. None of the patients discontinued their medications due to COVID-19. Compared to pediatric patients with IBD, a higher proportion of pediatric LT recipients reported fears of contracting severe COVID-19 infection due to their illness or medications (45, 59.2% vs. 110, 45.1%). Conclusion: Among pediatric LT recipients a higher proportion reported fear of severe COVID-19 infection, implemented additional protective measures and expressed a need for emotional support, compared to patients with IBD. Medical teams should provide adequate information and offer a support system for this vulnerable population.

Original languageEnglish
Article numbere14250
Pages (from-to)e14250
JournalPediatric Transplantation
Issue number4
StatePublished - 1 Jun 2022


  • COVID-19
  • Child
  • Cross-Sectional Studies
  • Humans
  • Inflammatory Bowel Diseases
  • Liver Transplantation/methods
  • Pandemics
  • SARS-CoV-2
  • Transplant Recipients/psychology
  • Treatment Adherence and Compliance
  • coronavirus disease
  • healthcare
  • liver transplantation
  • tele-health

All Science Journal Classification (ASJC) codes

  • Transplantation
  • Pediatrics, Perinatology, and Child Health


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