Transient precursor amorphous phases in biomineralization. In the footsteps of Heinz A. Lowenstam

Lia Addadi; Netta Vidavsky; Stephen Weiner

doi:10.1524/zkri.2012.1524

Transient precursor amorphous phases in biomineralization. In the footsteps of Heinz A. Lowenstam

Lia Addadi, Netta Vidavsky, Stephen Weiner

Department of Chemical and Structural Biology

Weizmann Institute of Science

Research output: Contribution to journal › Article › peer-review

Abstract

Heinz A. Lowenstam's discovery in 1967, together with Ken Towe that the magnetite mineral in mature chiton teeth forms from a disordered transient precursor phase, ferrihydrite, remained an isolated curiosity for 30 years. During the last 15 years, many more examples were found in both invertebrates and vertebrates, where the mature crystalline mineral phase is formed through a transient amorphous precursor phase. Here we review this widespread phenomenon, and also describe the details of the transformation process in the formation of the calcitic spicules of the sea urchin larva.We identify many open questions.

Original language	English
Pages (from-to)	711-717
Number of pages	7
Journal	Zeitschrift Fur Kristallographie
Volume	227
Issue number	11
DOIs	https://doi.org/10.1524/zkri.2012.1524
State	Published - 1 Nov 2012

Keywords

Amorphous phase
Biomineralization
Calcium carbonate
Sea urchin spicule
Transient precursor phase

All Science Journal Classification (ASJC) codes

Condensed Matter Physics
General Materials Science
Inorganic Chemistry

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10.1524/zkri.2012.1524

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title = "Transient precursor amorphous phases in biomineralization. In the footsteps of Heinz A. Lowenstam",

abstract = "Heinz A. Lowenstam's discovery in 1967, together with Ken Towe that the magnetite mineral in mature chiton teeth forms from a disordered transient precursor phase, ferrihydrite, remained an isolated curiosity for 30 years. During the last 15 years, many more examples were found in both invertebrates and vertebrates, where the mature crystalline mineral phase is formed through a transient amorphous precursor phase. Here we review this widespread phenomenon, and also describe the details of the transformation process in the formation of the calcitic spicules of the sea urchin larva.We identify many open questions.",

keywords = "Amorphous phase, Biomineralization, Calcium carbonate, Sea urchin spicule, Transient precursor phase",

author = "Lia Addadi and Netta Vidavsky and Stephen Weiner",

note = "Deutsche Forschungsgemeinschaft DIP Programme grant; use Katz Institute for Material Sciences at WISWe thank Julia Mahamid for providing some of the cryo-SEM micrographs. This work was supported by a Deutsche Forschungsgemeinschaft DIP Programme grant and by the use Katz Institute for Material Sciences at WIS. L.A. is the incumbent of the Dorothy and Patrick Gorman Professorial Chair of Biological Ultrastructure, and S.W. of the Dr. Trude Burchardt Professorial Chair of Structural Biology.",

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doi = "10.1524/zkri.2012.1524",

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AU - Addadi, Lia

AU - Vidavsky, Netta

AU - Weiner, Stephen

N1 - Deutsche Forschungsgemeinschaft DIP Programme grant; use Katz Institute for Material Sciences at WISWe thank Julia Mahamid for providing some of the cryo-SEM micrographs. This work was supported by a Deutsche Forschungsgemeinschaft DIP Programme grant and by the use Katz Institute for Material Sciences at WIS. L.A. is the incumbent of the Dorothy and Patrick Gorman Professorial Chair of Biological Ultrastructure, and S.W. of the Dr. Trude Burchardt Professorial Chair of Structural Biology.

PY - 2012/11/1

Y1 - 2012/11/1

N2 - Heinz A. Lowenstam's discovery in 1967, together with Ken Towe that the magnetite mineral in mature chiton teeth forms from a disordered transient precursor phase, ferrihydrite, remained an isolated curiosity for 30 years. During the last 15 years, many more examples were found in both invertebrates and vertebrates, where the mature crystalline mineral phase is formed through a transient amorphous precursor phase. Here we review this widespread phenomenon, and also describe the details of the transformation process in the formation of the calcitic spicules of the sea urchin larva.We identify many open questions.

AB - Heinz A. Lowenstam's discovery in 1967, together with Ken Towe that the magnetite mineral in mature chiton teeth forms from a disordered transient precursor phase, ferrihydrite, remained an isolated curiosity for 30 years. During the last 15 years, many more examples were found in both invertebrates and vertebrates, where the mature crystalline mineral phase is formed through a transient amorphous precursor phase. Here we review this widespread phenomenon, and also describe the details of the transformation process in the formation of the calcitic spicules of the sea urchin larva.We identify many open questions.

KW - Amorphous phase

KW - Biomineralization

KW - Calcium carbonate

KW - Sea urchin spicule

KW - Transient precursor phase

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U2 - 10.1524/zkri.2012.1524

DO - 10.1524/zkri.2012.1524

M3 - مقالة

SN - 0044-2968

VL - 227

SP - 711

EP - 717

JO - Zeitschrift Fur Kristallographie

JF - Zeitschrift Fur Kristallographie

IS - 11

ER -

Transient precursor amorphous phases in biomineralization. In the footsteps of Heinz A. Lowenstam

Abstract

Keywords

All Science Journal Classification (ASJC) codes

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