Trajectories of Symptom Severity in Children with Autism: Variability and Turning Points through the Transition to School

Stelios Georgiades; Peter A. Tait; Paul D. McNicholas; Eric Duku; Lonnie Zwaigenbaum; Isabel M. Smith; Teresa Bennett; Mayada Elsabbagh; Connor M. Kerns; Pat Mirenda; Wendy J. Ungar; Tracy Vaillancourt; Joanne Volden; Charlotte Waddell; Anat Zaidman-Zait; Stephen Gentles; Peter Szatmari

doi:10.1007/s10803-021-04949-2

Trajectories of Symptom Severity in Children with Autism: Variability and Turning Points through the Transition to School

Stelios Georgiades, Peter A. Tait, Paul D. McNicholas, Eric Duku, Lonnie Zwaigenbaum, Isabel M. Smith, Teresa Bennett, Mayada Elsabbagh, Connor M. Kerns, Pat Mirenda, Wendy J. Ungar, Tracy Vaillancourt, Joanne Volden, Charlotte Waddell, Anat Zaidman-Zait, Stephen Gentles, Peter Szatmari

School of Education

Tel Aviv University

Research output: Contribution to journal › Article › peer-review

Abstract

This study examined the trajectories of autistic symptom severity in an inception cohort of 187 children with ASD assessed across four time points from diagnosis to age 10. Trajectory groups were derived using multivariate cluster analysis. A two trajectory/cluster solution was selected. Change in trajectory slopes revealed a turning point marked by plateauing in symptom reduction during the period of transition to school (age 6) for one of the two trajectories. Trajectories were labelled: Continuously Improving (27%) and Improving then Plateauing (73% of sample). Children in the two trajectories differed in levels of symptom severity, language, cognitive, and adaptive functioning skills. Study findings can inform the development of more personalized services for children with ASD transitioning into the school system.

Original language	English
Pages (from-to)	392-401
Number of pages	10
Journal	Journal of Autism and Developmental Disorders
Volume	52
Issue number	1
DOIs	https://doi.org/10.1007/s10803-021-04949-2
State	Published - Jan 2022

Keywords

Autism spectrum disorder
Chronogeneity
Trajectories
Turning points

All Science Journal Classification (ASJC) codes

Developmental and Educational Psychology

Access to Document

10.1007/s10803-021-04949-2

Cite this

Georgiades, S., Tait, P. A., McNicholas, P. D., Duku, E., Zwaigenbaum, L., Smith, I. M., Bennett, T., Elsabbagh, M., Kerns, C. M., Mirenda, P., Ungar, W. J., Vaillancourt, T., Volden, J., Waddell, C., Zaidman-Zait, A., Gentles, S., & Szatmari, P. (2022). Trajectories of Symptom Severity in Children with Autism: Variability and Turning Points through the Transition to School. Journal of Autism and Developmental Disorders, 52(1), 392-401. https://doi.org/10.1007/s10803-021-04949-2

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title = "Trajectories of Symptom Severity in Children with Autism: Variability and Turning Points through the Transition to School",

abstract = "This study examined the trajectories of autistic symptom severity in an inception cohort of 187 children with ASD assessed across four time points from diagnosis to age 10. Trajectory groups were derived using multivariate cluster analysis. A two trajectory/cluster solution was selected. Change in trajectory slopes revealed a turning point marked by plateauing in symptom reduction during the period of transition to school (age 6) for one of the two trajectories. Trajectories were labelled: Continuously Improving (27%) and Improving then Plateauing (73% of sample). Children in the two trajectories differed in levels of symptom severity, language, cognitive, and adaptive functioning skills. Study findings can inform the development of more personalized services for children with ASD transitioning into the school system.",

keywords = "Autism spectrum disorder, Chronogeneity, Trajectories, Turning points",

author = "Stelios Georgiades and Tait, {Peter A.} and McNicholas, {Paul D.} and Eric Duku and Lonnie Zwaigenbaum and Smith, {Isabel M.} and Teresa Bennett and Mayada Elsabbagh and Kerns, {Connor M.} and Pat Mirenda and Ungar, {Wendy J.} and Tracy Vaillancourt and Joanne Volden and Charlotte Waddell and Anat Zaidman-Zait and Stephen Gentles and Peter Szatmari",

note = "Publisher Copyright: {\textcopyright} 2021, The Author(s).",

year = "2022",

month = jan,

doi = "10.1007/s10803-021-04949-2",

language = "الإنجليزيّة",

volume = "52",

pages = "392--401",

journal = "Journal of Autism and Developmental Disorders",

issn = "0162-3257",

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number = "1",

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Georgiades, S, Tait, PA, McNicholas, PD, Duku, E, Zwaigenbaum, L, Smith, IM, Bennett, T, Elsabbagh, M, Kerns, CM, Mirenda, P, Ungar, WJ, Vaillancourt, T, Volden, J, Waddell, C, Zaidman-Zait, A, Gentles, S & Szatmari, P 2022, 'Trajectories of Symptom Severity in Children with Autism: Variability and Turning Points through the Transition to School', Journal of Autism and Developmental Disorders, vol. 52, no. 1, pp. 392-401. https://doi.org/10.1007/s10803-021-04949-2

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T1 - Trajectories of Symptom Severity in Children with Autism

T2 - Variability and Turning Points through the Transition to School

AU - Georgiades, Stelios

AU - Tait, Peter A.

AU - McNicholas, Paul D.

AU - Duku, Eric

AU - Zwaigenbaum, Lonnie

AU - Smith, Isabel M.

AU - Bennett, Teresa

AU - Elsabbagh, Mayada

AU - Kerns, Connor M.

AU - Mirenda, Pat

AU - Ungar, Wendy J.

AU - Vaillancourt, Tracy

AU - Volden, Joanne

AU - Waddell, Charlotte

AU - Zaidman-Zait, Anat

AU - Gentles, Stephen

AU - Szatmari, Peter

PY - 2022/1

Y1 - 2022/1

N2 - This study examined the trajectories of autistic symptom severity in an inception cohort of 187 children with ASD assessed across four time points from diagnosis to age 10. Trajectory groups were derived using multivariate cluster analysis. A two trajectory/cluster solution was selected. Change in trajectory slopes revealed a turning point marked by plateauing in symptom reduction during the period of transition to school (age 6) for one of the two trajectories. Trajectories were labelled: Continuously Improving (27%) and Improving then Plateauing (73% of sample). Children in the two trajectories differed in levels of symptom severity, language, cognitive, and adaptive functioning skills. Study findings can inform the development of more personalized services for children with ASD transitioning into the school system.

AB - This study examined the trajectories of autistic symptom severity in an inception cohort of 187 children with ASD assessed across four time points from diagnosis to age 10. Trajectory groups were derived using multivariate cluster analysis. A two trajectory/cluster solution was selected. Change in trajectory slopes revealed a turning point marked by plateauing in symptom reduction during the period of transition to school (age 6) for one of the two trajectories. Trajectories were labelled: Continuously Improving (27%) and Improving then Plateauing (73% of sample). Children in the two trajectories differed in levels of symptom severity, language, cognitive, and adaptive functioning skills. Study findings can inform the development of more personalized services for children with ASD transitioning into the school system.

KW - Autism spectrum disorder

KW - Chronogeneity

KW - Trajectories

KW - Turning points

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Trajectories of Symptom Severity in Children with Autism: Variability and Turning Points through the Transition to School

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Keywords

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