Abstract
Oncogene expression can lead to replication stress and genome instability. Recently, we identified oncogene-induced fragile sites (FSs) and revealed that the landscape of recurrent fragility in the same cell type is dynamic. This implies an additional level of complexity in the molecular basis of recurrent fragility in cancer.
| Original language | English |
|---|---|
| Article number | e1072657 |
| Journal | Molecular and Cellular Oncology |
| Volume | 3 |
| Issue number | 1 |
| DOIs | |
| State | Published - 2 Jan 2016 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Cancer breakage
- fragile sites
- genome instability
- oncogene expression
- recurrent fragility
- replication stress
ASJC Scopus subject areas
- Molecular Medicine
- Cancer Research
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