Time-dependent gene expression analysis of the developing superior olivary complex

Heike Ehmann; Heiner Hartwich; Christian Salzig; Nadja Hartmann; Mathieu Clement-Ziza; Kathy Ushakov; Karen B. Avraham; Olaf R.P. Bininda-Emonds; Alexander K. Hartmann; Patrick Lang; Eckhard Friauf; Hans Gerd Nothwang

doi:10.1074/jbc.M113.490508

Time-dependent gene expression analysis of the developing superior olivary complex

Heike Ehmann, Heiner Hartwich, Christian Salzig, Nadja Hartmann, Mathieu Clement-Ziza, Kathy Ushakov, Karen B. Avraham, Olaf R.P. Bininda-Emonds, Alexander K. Hartmann, Patrick Lang, Eckhard Friauf, Hans Gerd Nothwang

Human Molecular Genetics Biochemistry

Tel Aviv University

Research output: Contribution to journal › Article › peer-review

Abstract

Background: The superior olivary complex (SOC) is an essential center for spatial hearing. Results: Generation of a comprehensive qualitative and quantitative catalogue of the developmental changes in the SOC-related gene repertoire. Conclusion: Postnatal maturation of the SOC is shaped by extensive molecular changes. Significance: This work identifies strong candidate genes for normal and impaired hearing and genetic evidence for retrocochlear functions of deafness genes.

Original language	English
Pages (from-to)	25865-25879
Number of pages	15
Journal	Journal of Biological Chemistry
Volume	288
Issue number	36
DOIs	https://doi.org/10.1074/jbc.M113.490508
State	Published - 6 Sep 2013

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Biology
Cell Biology

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10.1074/jbc.M113.490508

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title = "Time-dependent gene expression analysis of the developing superior olivary complex",

abstract = "Background: The superior olivary complex (SOC) is an essential center for spatial hearing. Results: Generation of a comprehensive qualitative and quantitative catalogue of the developmental changes in the SOC-related gene repertoire. Conclusion: Postnatal maturation of the SOC is shaped by extensive molecular changes. Significance: This work identifies strong candidate genes for normal and impaired hearing and genetic evidence for retrocochlear functions of deafness genes.",

author = "Heike Ehmann and Heiner Hartwich and Christian Salzig and Nadja Hartmann and Mathieu Clement-Ziza and Kathy Ushakov and Avraham, {Karen B.} and Bininda-Emonds, {Olaf R.P.} and Hartmann, {Alexander K.} and Patrick Lang and Eckhard Friauf and Nothwang, {Hans Gerd}",

year = "2013",

month = sep,

day = "6",

doi = "10.1074/jbc.M113.490508",

language = "الإنجليزيّة",

volume = "288",

pages = "25865--25879",

journal = "Journal of Biological Chemistry",

issn = "0021-9258",

publisher = "American Society for Biochemistry and Molecular Biology Inc.",

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T1 - Time-dependent gene expression analysis of the developing superior olivary complex

AU - Ehmann, Heike

AU - Hartwich, Heiner

AU - Salzig, Christian

AU - Hartmann, Nadja

AU - Clement-Ziza, Mathieu

AU - Ushakov, Kathy

AU - Avraham, Karen B.

AU - Bininda-Emonds, Olaf R.P.

AU - Hartmann, Alexander K.

AU - Lang, Patrick

AU - Friauf, Eckhard

AU - Nothwang, Hans Gerd

PY - 2013/9/6

Y1 - 2013/9/6

N2 - Background: The superior olivary complex (SOC) is an essential center for spatial hearing. Results: Generation of a comprehensive qualitative and quantitative catalogue of the developmental changes in the SOC-related gene repertoire. Conclusion: Postnatal maturation of the SOC is shaped by extensive molecular changes. Significance: This work identifies strong candidate genes for normal and impaired hearing and genetic evidence for retrocochlear functions of deafness genes.

AB - Background: The superior olivary complex (SOC) is an essential center for spatial hearing. Results: Generation of a comprehensive qualitative and quantitative catalogue of the developmental changes in the SOC-related gene repertoire. Conclusion: Postnatal maturation of the SOC is shaped by extensive molecular changes. Significance: This work identifies strong candidate genes for normal and impaired hearing and genetic evidence for retrocochlear functions of deafness genes.

UR - http://www.scopus.com/inward/record.url?scp=84883733414&partnerID=8YFLogxK

U2 - 10.1074/jbc.M113.490508

DO - 10.1074/jbc.M113.490508

M3 - مقالة

SN - 0021-9258

VL - 288

SP - 25865

EP - 25879

JO - Journal of Biological Chemistry

JF - Journal of Biological Chemistry

IS - 36

ER -

Time-dependent gene expression analysis of the developing superior olivary complex

Abstract

All Science Journal Classification (ASJC) codes

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