TY - JOUR
T1 - The role of oxytocin in regulating loneliness in old age
AU - Abu Elheja, R.
AU - Palgi, Y.
AU - Feldman, R.
AU - Zagoory-Sharon, O.
AU - Keisari, S.
AU - Shamay-Tsoory, S. G.
N1 - Funding Information: This work was supported by PisgotCarmel Community Organization , Isreal and by a research grant from the Jewish-Arab Center (JAC) at the University of Haifa , Israel. Funding Information: This work was supported by PisgotCarmel Community Organization, Isreal and by a research grant from the Jewish-Arab Center (JAC) at the University of Haifa, Israel. Publisher Copyright: © 2021 Elsevier Ltd
PY - 2021/11
Y1 - 2021/11
N2 - Loneliness is prevalent in old age and is associated with reduced positive social interactions. Building on studies showing that oxytocin (OT) levels rise during social interactions, we hypothesized that following participation in positive social interaction involving synchronized movements, OT levels would increase, while state loneliness levels would diminish. A total of 63 older adults (aged M = 78.93, SD = 9.99; Range = 65–101) participated in the study. Participants completed emotional and social loneliness scales and provided saliva samples pre- and post-participation in the “mirror game”, which requires movement synchronization and is known to promote connectedness and closeness. Results indicate a reduced state of loneliness following the mirror game. Importantly, the change in OT levels predicted the change in social loneliness, defined as the absence of social interactions with people in the social network. On the other hand, emotional loneliness, marked by deficient emotional contact, only decreased among participants who experienced high levels of closeness with their partner in the mirror game. Findings suggest that context-dependent change in endogenous OT may serve as biomarker for the social effects of oxytocin on loneliness in old age and can help in the development of targeted interventions for treating loneliness in old age.
AB - Loneliness is prevalent in old age and is associated with reduced positive social interactions. Building on studies showing that oxytocin (OT) levels rise during social interactions, we hypothesized that following participation in positive social interaction involving synchronized movements, OT levels would increase, while state loneliness levels would diminish. A total of 63 older adults (aged M = 78.93, SD = 9.99; Range = 65–101) participated in the study. Participants completed emotional and social loneliness scales and provided saliva samples pre- and post-participation in the “mirror game”, which requires movement synchronization and is known to promote connectedness and closeness. Results indicate a reduced state of loneliness following the mirror game. Importantly, the change in OT levels predicted the change in social loneliness, defined as the absence of social interactions with people in the social network. On the other hand, emotional loneliness, marked by deficient emotional contact, only decreased among participants who experienced high levels of closeness with their partner in the mirror game. Findings suggest that context-dependent change in endogenous OT may serve as biomarker for the social effects of oxytocin on loneliness in old age and can help in the development of targeted interventions for treating loneliness in old age.
KW - Emotional loneliness
KW - Mirror game
KW - Oxytocin
KW - Social loneliness
KW - Synchronization
UR - http://www.scopus.com/inward/record.url?scp=85115381869&partnerID=8YFLogxK
U2 - https://doi.org/10.1016/j.psyneuen.2021.105413
DO - https://doi.org/10.1016/j.psyneuen.2021.105413
M3 - Article
C2 - 34563837
SN - 0306-4530
VL - 133
JO - Psychoneuroendocrinology
JF - Psychoneuroendocrinology
M1 - 105413
ER -