The remedy within: will the microbiome fulfill its therapeutic promise?

Christoph A. Thaiss, Eran Elinav

Research output: Contribution to journalReview articlepeer-review


The last decade of research has witnessed a tremendous upsurge in our understanding of the intestinal microbiome and its role in a large range of human diseases, which has incited hopes for a rapid clinical utilization of the new insights for the development of microbiome-based therapies. Nonetheless, only a single microbiome-targeted therapy has so far found its way into clinical routine: fecal microbiota transplantation for patients suffering from recurrent Clostridium difficile infections. Herein, we discuss the current hopes, advances, challenges, and obstacles for translating basic microbiome research into therapeutic applications for a larger number of diseases and provide an outline of how such clinical applications might emerge.

Original languageEnglish
Pages (from-to)1021-1027
Number of pages7
JournalJournal of Molecular Medicine
Issue number10
StatePublished - 1 Oct 2017

All Science Journal Classification (ASJC) codes

  • Drug Discovery
  • Genetics(clinical)
  • Molecular Medicine


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