The israeli phage bank (IPB)

Ortal Yerushalmy, Leron Khalifa, Naama Gold, Chani Rakov, Sivan Alkalay-Oren, Karen Adler, Shira Ben-Porat, Reut Kraitman, Niv Gronovich, Kerem Shulamit Ginat, Mohanad Abdalrhman, Shunit Coppenhagen-Glazer, Ran Nir-Paz, Ronen Hazan

Research output: Contribution to journalArticlepeer-review

Abstract

A key element in phage therapy is the establishment of large phage collections, termed herein “banks”, where many well-characterized phages, ready to be used in the clinic, are stored. These phage banks serve for both research and clinical purposes. Phage banks are also a key element in clinical phage microbiology, the prior treatment matching of phages and antibiotics to specific bacterial targets. A worldwide network of phage banks can promote a phage-based solution for any isolated bacteria. Herein, we describe the Israeli Phage Bank (IPB) established in the Hebrew University, Jerusalem, which currently has over 300 phages matching 16 bacteria, mainly pathogens. The phage bank is constantly isolating new phages and developing methods for phage isolation and characterization. The information on the phages and bacteria stored in the bank is available online.

Original languageEnglish
Article number269
JournalAntibiotics
Volume9
Issue number5
DOIs
StatePublished - May 2020

Keywords

  • Bacteriophage
  • IBP
  • Phage bank
  • Phage database
  • Phage therapy

All Science Journal Classification (ASJC) codes

  • General Pharmacology, Toxicology and Pharmaceutics
  • Microbiology (medical)
  • Infectious Diseases
  • Pharmacology (medical)
  • Biochemistry
  • Microbiology

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