The integral role of CD74 in antigen presentation, MIF signal transduction, and B cell survival and homeostasis

R Bucala; Idit Shachar

doi:10.2174/1389557515666150203144111

The integral role of CD74 in antigen presentation, MIF signal transduction, and B cell survival and homeostasis

R Bucala, Idit Shachar

Department of Systems Immunology

Weizmann Institute of Science

Research output: Contribution to journal › Article › peer-review

Abstract

Molecules that link innate and adaptive immunity and regulate immune response in health and disease are now the focus of many studies. This review discusses CD74 and its ligand macrophage migration inhibitory factor (MIF), and. their central position in linking these two components of the immune response by controlling survival of macrophages and. B cells.

Original language	English
Pages (from-to)	1132-1138
Number of pages	7
Journal	Mini-Reviews in Medicinal Chemistry
Volume	14
Issue number	14
DOIs	https://doi.org/10.2174/1389557515666150203144111
State	Published - 1 May 2014

All Science Journal Classification (ASJC) codes

Molecular Medicine
Pharmacology
Drug Discovery
Cancer Research

Access to Document

10.2174/1389557515666150203144111

Cite this

@article{2fd04d86187e4cf4842550adf1f7fb9d,

title = "The integral role of CD74 in antigen presentation, MIF signal transduction, and B cell survival and homeostasis",

abstract = "Molecules that link innate and adaptive immunity and regulate immune response in health and disease are now the focus of many studies. This review discusses CD74 and its ligand macrophage migration inhibitory factor (MIF), and. their central position in linking these two components of the immune response by controlling survival of macrophages and. B cells.",

author = "R Bucala and Idit Shachar",

note = "Publisher Copyright: {\textcopyright} 2014 Bentham Science Publishers",

year = "2014",

month = may,

day = "1",

doi = "10.2174/1389557515666150203144111",

language = "الإنجليزيّة",

volume = "14",

pages = "1132--1138",

journal = "Mini-Reviews in Medicinal Chemistry",

issn = "1389-5575",

publisher = "Bentham Science Publishers",

number = "14",

}

TY - JOUR

T1 - The integral role of CD74 in antigen presentation, MIF signal transduction, and B cell survival and homeostasis

AU - Bucala, R

AU - Shachar, Idit

PY - 2014/5/1

Y1 - 2014/5/1

N2 - Molecules that link innate and adaptive immunity and regulate immune response in health and disease are now the focus of many studies. This review discusses CD74 and its ligand macrophage migration inhibitory factor (MIF), and. their central position in linking these two components of the immune response by controlling survival of macrophages and. B cells.

AB - Molecules that link innate and adaptive immunity and regulate immune response in health and disease are now the focus of many studies. This review discusses CD74 and its ligand macrophage migration inhibitory factor (MIF), and. their central position in linking these two components of the immune response by controlling survival of macrophages and. B cells.

UR - http://www.scopus.com/inward/record.url?scp=84924907141&partnerID=8YFLogxK

U2 - 10.2174/1389557515666150203144111

DO - 10.2174/1389557515666150203144111

M3 - مقالة

SN - 1389-5575

VL - 14

SP - 1132

EP - 1138

JO - Mini-Reviews in Medicinal Chemistry

JF - Mini-Reviews in Medicinal Chemistry

IS - 14

ER -

The integral role of CD74 in antigen presentation, MIF signal transduction, and B cell survival and homeostasis

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this