The Integral Role of CD74 in Antigen Presentation, MIF Signal Transduction, and B Cell Survival and Homeostasis

R Bucala, Idit Shachar

Research output: Contribution to journalReview articlepeer-review

Abstract

Molecules that link innate and adaptive immunity and regulate immune response in health and disease are now the focus of many studies. This review discusses CD74 and its ligand macrophage migration inhibitory factor (MIF), and their central position in linking these two components of the immune response by controlling survival of macrophages and B cells.
Original languageEnglish
Pages (from-to)1132-1138
Number of pages7
JournalMini-Reviews in Medicinal Chemistry
Volume14
Issue number14
StatePublished - 2014

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