The environmentally benign form of pesticide in hydrodispersive nanometric form with improved efficacy against adult mosquitoes at low exposure concentrations

A. P.B. Balaji, Prabhakar Mishra, R. S. Suresh Kumar, Abhijeet Ashu, Katherine Margulis, Shlomo Magdassi, Amitava Mukherjee, Natarajan Chandrasekaran

Research output: Contribution to journalArticlepeer-review

Abstract

Permethrin, a poorly water-soluble synthetic pesticide belonging to the pyrethroid family, was formulated into water-dispersive nanometric form by rapid evaporation of pesticide loaded oil-in-water microemulsion. The mean hydrodynamic diameter of Nanopermethrin was found to be 199.01 ± 1.4 nm. The efficacy of the Nanopermethrin was comparatively investigated with its bulk form against 2-3 days old adult mosquitoes by WHO cone bioassay for 60 min. The median knockdown concentration of Culex tritaeniorhynchus, Culex quinquefasciatus and Aedes albopictus were found to be 7.20 × 104, 7.53 × 104, 0.42 × 103 mg/L for Bulk permethrin, and 0.98 × 104, 1.17 × 104, 0.05 × 103 mg/L for Nanopermethrin, respectively. The obtained results extrapolate the improved efficacy of Nanopermethrin even at low-level concentrations. Hence, the formulated Nanopermethrin will serve as an effective alternative pesticide in controlling the mosquito population with reduced environmental toxicity.

Original languageAmerican English
Pages (from-to)734-739
Number of pages6
JournalBulletin of Environmental Contamination and Toxicology
Volume95
Issue number6
DOIs
StatePublished - 1 Dec 2015

Keywords

  • Contact toxicity
  • Environmental safety
  • Knockdown
  • Nanopesticide
  • Permethrin
  • WHO cone bioassay

All Science Journal Classification (ASJC) codes

  • Toxicology
  • Pollution
  • Health, Toxicology and Mutagenesis

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