@article{ebb9d52d7e7b488ba51427c90290d6b0,
title = "The distribution of cellular turnover in the human body",
abstract = "We integrated ubiquity, mass and lifespan of all major cell types to achieve a comprehensive quantitative description of cellular turnover. We found a total cellular mass turnover of 80 ± 20 grams per day, dominated by blood cells and gut epithelial cells. In terms of cell numbers, close to 90% of the (0.33 ± 0.02) × 1012 cells per day turnover was blood cells.",
author = "Ron Sender and Ron Milo",
note = "We thank Y. Bar-on, Y. Beit-Yannai, J. Brown, Y. Dor, A. Egozi, A. Erez, G. Eshel, S. Fuchs, D. Gluck, L. Greenspoon, D. Hochhauser, S. Itzkovitz, E. Krieger, R. Phillips, R. Scherz-Shouval, L. Shachar, I. Shavitt, L. Shlush, A. Tendler and A. Wides for helpful discussions. This research was supported by the European Research Council (project NOVCARBFIX 646827), Israel Science Foundation (grant 740/16), Beck-Canadian Center for Alternative Energy Research, Dana and Yossie Hollander, Ullmann Family Foundation, Helmsley Charitable Foundation, Larson Charitable Foundation, Wolfson Family Charitable Trust, Charles Rothschild, Selmo Nussenbaum (R.M.), the Israeli Council for Higher Education via the Weizmann Data Science Research Center and by a research grant from Madame Olga Klein – Astrachan (R.S.). R.M. is the Charles and Louise Gartner Professional Chair. Contributions - R.S. and R.M. conceived and performed the study and wrote the manuscript.",
year = "2021",
month = jan,
doi = "10.1038/s41591-020-01182-9",
language = "الإنجليزيّة",
volume = "27",
pages = "45--48",
journal = "Nature Medicine",
issn = "1078-8956",
publisher = "Nature Research",
number = "1",
}