The development and application of optogenetics

Lief Fenno; Ofer Yizhar; Karl Deisseroth

doi:https://doi.org/10.1146/annurev-neuro-061010-113817

The development and application of optogenetics

Lief Fenno, Ofer Yizhar, Karl Deisseroth

Research output: Contribution to journal › Article › peer-review

Abstract

Genetically encoded, single-component optogenetic tools have made a significant impact on neuroscience, enabling specific modulation of selected cells within complex neural tissues. As the optogenetic toolbox contents grow and diversify, the opportunities for neuroscience continue to grow. In this review, we outline the development of currently available single-component optogenetic tools and summarize the application of various optogenetic tools in diverse model organisms.

Original language	English
Pages (from-to)	389-412
Number of pages	24
Journal	Annual Review of Neuroscience
Volume	34
DOIs	https://doi.org/10.1146/annurev-neuro-061010-113817
State	Published - 21 Jul 2011
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Neuroscience

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https://doi.org/10.1146/annurev-neuro-061010-113817

Cite this

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The development and application of optogenetics

Abstract

All Science Journal Classification (ASJC) codes

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