TY - JOUR
T1 - The characteristics and pattern of care for the type 2 diabetes mellitus population in the MENA region during Ramadan
T2 - An international prospective study (DAR-MENA T2DM)
AU - Hassanein, Mohamed
AU - Al Awadi, Fatheya F.
AU - El Hadidy, Khaled El Sayed
AU - Ali, Sobia Sabir
AU - Echtay, Akram
AU - Djaballah, Khier
AU - Dessapt-Baradez, Cecile
AU - Khazaal, Faris Abdul Kareem
AU - Abu-Hijleh, Mohamad Omar
AU - Al Shaikh, Abdulrahman
AU - Gharbi, Mohamed El Hassan
AU - Shehadeh, Naim
AU - Bennakhi, Abdullah
AU - Al Arouj, Monira
N1 - Publisher Copyright: © 2019 The Authors
PY - 2019/5
Y1 - 2019/5
N2 - Aims: We aimed to describe the characteristics and care of participants with diabetes during Ramadan in the Middle East and North Africa (MENA). Methods: In this prospective, observational study, we analysed the number of fasted days, number of participants fasting, glycemic control, rate of hypoglycemic events, and lifestyle patterns for participants with T2DM during Ramadan 2016. Results: The population included 1749 participants with T2DM. The mean (SD) duration of fasting was 27.7 (5.0) days, and 57.3% of participants fasted for the full duration of Ramadan. Following Ramadan, a significant improvement in HbA1c, FPG, and PPG was observed (p < 0.0001). Confirmed hypoglycemia increased significantly from before to during Ramadan (incidence: 4.9% vs. 10.4%, p < 0.001; adverse events: 0.11 vs. 0.22 events/month/participant, p < 0.001) and was dependent on the treatment regimen. Severe hypoglycemia incidence was 0.2% before versus 0.9% during Ramadan (p = 0.031), whereas adverse events remained comparable (0.01 events/month/participant; p = 0.154). Most participants (97.4%) reported lifestyle changes during Ramadan. Conclusions: This prospective study is the first to describe the characteristics and care of participants with T2DM during Ramadan in MENA, and can be utilized in the development of evidence-based care to ensure the safety of participants who fast.
AB - Aims: We aimed to describe the characteristics and care of participants with diabetes during Ramadan in the Middle East and North Africa (MENA). Methods: In this prospective, observational study, we analysed the number of fasted days, number of participants fasting, glycemic control, rate of hypoglycemic events, and lifestyle patterns for participants with T2DM during Ramadan 2016. Results: The population included 1749 participants with T2DM. The mean (SD) duration of fasting was 27.7 (5.0) days, and 57.3% of participants fasted for the full duration of Ramadan. Following Ramadan, a significant improvement in HbA1c, FPG, and PPG was observed (p < 0.0001). Confirmed hypoglycemia increased significantly from before to during Ramadan (incidence: 4.9% vs. 10.4%, p < 0.001; adverse events: 0.11 vs. 0.22 events/month/participant, p < 0.001) and was dependent on the treatment regimen. Severe hypoglycemia incidence was 0.2% before versus 0.9% during Ramadan (p = 0.031), whereas adverse events remained comparable (0.01 events/month/participant; p = 0.154). Most participants (97.4%) reported lifestyle changes during Ramadan. Conclusions: This prospective study is the first to describe the characteristics and care of participants with T2DM during Ramadan in MENA, and can be utilized in the development of evidence-based care to ensure the safety of participants who fast.
KW - Epidemiology
KW - Glycemic control
KW - Hypoglycemia
KW - Middle East and North Africa
KW - Ramadan fasting
KW - Type 2 diabetes mellitus
UR - http://www.scopus.com/inward/record.url?scp=85062967099&partnerID=8YFLogxK
U2 - https://doi.org/10.1016/j.diabres.2019.02.020
DO - https://doi.org/10.1016/j.diabres.2019.02.020
M3 - مقالة
C2 - 30825560
SN - 0168-8227
VL - 151
SP - 275
EP - 284
JO - Diabetes Research and Clinical Practice
JF - Diabetes Research and Clinical Practice
ER -