Abstract
Revealing how the core pluripotency circuitry is orchestrated to maintain the ground state of embryonic stem cells (ESCs) is fundamental for understanding self-renewal and early lineage specifications. In this issue of Cell Stem Cell, Ding et al. (2015) identify a new Sox2-interacting protein, Tex10, which, together with Tet1 and p300, regulate super-enhancers to sustain pluripotency.
Original language | English |
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Pages (from-to) | 572-573 |
Number of pages | 2 |
Journal | Cell Stem Cell |
Volume | 16 |
Issue number | 6 |
DOIs | |
State | Published - 4 Jun 2015 |
All Science Journal Classification (ASJC) codes
- Molecular Medicine
- Genetics
- Cell Biology