TY - JOUR
T1 - Synthetic and Predictive Approach to Unsymmetrical Biphenols by Iron-Catalyzed Chelated Radical-Anion Oxidative Coupling
AU - Libman, Anna
AU - Shalit, Hadas
AU - Vainer, Yulia
AU - Narute, Sachin
AU - Kozuch, Sebastian
AU - Pappo, Doron
N1 - Publisher Copyright: © 2015 American Chemical Society.
PY - 2015/9/9
Y1 - 2015/9/9
N2 - An iron-catalyzed oxidative unsymmetrical biphenol coupling in 1,1,1,3,3,3-hexafluoropropan-2-ol that proceeds via a chelated radical-anion coupling mechanism was developed. Based on mechanistic studies, electrochemical methods, and density functional theory calculations, we suggest a general model that enables prediction of the feasibility of cross-coupling for a given pair of phenols.
AB - An iron-catalyzed oxidative unsymmetrical biphenol coupling in 1,1,1,3,3,3-hexafluoropropan-2-ol that proceeds via a chelated radical-anion coupling mechanism was developed. Based on mechanistic studies, electrochemical methods, and density functional theory calculations, we suggest a general model that enables prediction of the feasibility of cross-coupling for a given pair of phenols.
UR - http://www.scopus.com/inward/record.url?scp=84941236830&partnerID=8YFLogxK
U2 - https://doi.org/10.1021/jacs.5b06494
DO - https://doi.org/10.1021/jacs.5b06494
M3 - Article
C2 - 26287435
SN - 0002-7863
VL - 137
SP - 11453
EP - 11460
JO - Journal of the American Chemical Society
JF - Journal of the American Chemical Society
IS - 35
ER -