Symmetry-based analysis of diffusion MRI for the detection of brain impairments

O. A. Gorodissky, A. Sharon, A. Danov, A. Friedman, T. Riklin Raviv

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

We present a novel computational approach to detect white-matter brain impairments following stroke or Traumatic Brain Injuries (TBI). A key assumption in our study is that the two hemispheres are not affected identically. The pathology of white matter (WM) tracts can be thus identified according to the asymmetry level of brain diffusivity measures, such as Fractional Anisotropy (FA) and Mean Diffusivity (MD), extracted from Diffusion Tensor Imaging (DTI). The proposed methodological contribution is based on the construction of a sequence of isosurfaces of these scalar measures and their symmetrical counterparts, obtained by reflecting the original isosurfaces. The modified Hausdorff distance is then used to measure the dissimilarity between each corresponding pair of aligned surfaces. The proposed method is assessed using datasets of normal controls (NCs), stroke patients and longitudinal brain scans of football players that might have been exposed to mild head traumas. Increased asymmetry with respect to NCs is shown for the stroke patients and some of the players indicating possible WM injuries.

Original languageAmerican English
Title of host publication2018 IEEE International Conference on Image Processing, ICIP 2018 - Proceedings
Pages376-379
Number of pages4
ISBN (Electronic)9781479970612
DOIs
StatePublished - 29 Aug 2018
Event25th IEEE International Conference on Image Processing, ICIP 2018 - Athens, Greece
Duration: 7 Oct 201810 Oct 2018

Publication series

NameProceedings - International Conference on Image Processing, ICIP

Conference

Conference25th IEEE International Conference on Image Processing, ICIP 2018
Country/TerritoryGreece
CityAthens
Period7/10/1810/10/18

Keywords

  • Contact Sport players
  • DTI
  • Fractional Anisotropy
  • MRI
  • Mean Diffusion
  • Mild TBI
  • Shape dissimilarity
  • Symmetry

All Science Journal Classification (ASJC) codes

  • Software
  • Signal Processing
  • Computer Vision and Pattern Recognition

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