Streptococcus pyogenes sortase mutants are highly susceptible to killing by host factors due to aberrant envelope physiology

Medicine & Life Sciences

• Streptococcus pyogenes 91%
• Virulence Factors 78%
• sortase A 65%
• Bacterial Physiological Phenomena 55%
• CAP18 lipopolysaccharide-binding protein 54%
• Membranes 44%
• Gram-Positive Bacteria 41%
• Cell Wall 38%
• Membrane Proteins 31%
• Proteins 27%
• Amino Acids 26%
• Anti-Bacterial Agents 24%
• Infections 17%

Agriculture & Biology

• Streptococcus pyogenes 100%
• sorting 75%
• physiology 60%
• mutants 44%
• sortase A 27%
• virulence 24%
• cathelicidins 23%
• microbial physiology 22%
• surface proteins 17%
• Gram-positive bacteria 15%
• antibiotics 11%
• cell walls 10%
• toxicity 10%
• proteins 10%
• cells 9%
• pathogens 8%
• blood 8%
• amino acids 8%
• infection 7%

Chemistry

• Virulence Factor 69%
• Cathelicidin 42%
• Protein 31%
• Antibacterial Agent 27%
• Surface 15%
• Plasma 15%
• Environment 14%
• Reduction 11%
• Acid 8%