Step-emulsification in a microfluidic device

Z. Li; A. M. Leshansky; L. M. Pismen; P. Tabeling

doi:10.1039/c4lc01289e

Step-emulsification in a microfluidic device

Z. Li, A. M. Leshansky, L. M. Pismen, P. Tabeling

Technion - Israel Institute of Technology

Research output: Contribution to journal › Article › peer-review

Abstract

We present a comprehensive study of the step-emulsification process for high-throughput production of colloidal monodisperse droplets. The 'microfluidic step emulsifier' combines a shallow microchannel operating with two co-flowing immiscible fluids and an abrupt (step-like) opening to a deep and wide reservoir. Based on Hele-Shaw hydrodynamics, we determine the quasi-static shape of the fluid interface prior to transition to oscillatory step-emulsification at low capillary numbers. The theoretically derived transition threshold yields an excellent agreement with experimental data. A closed-form expression for the size of the droplets generated in the step-emulsification regime and derived using geometric arguments also shows a very good agreement with the experiment.

Original language	English
Pages (from-to)	1023-1031
Number of pages	9
Journal	Lab on a Chip
Volume	15
Issue number	4
DOIs	https://doi.org/10.1039/c4lc01289e
State	Published - 21 Feb 2015

All Science Journal Classification (ASJC) codes

Bioengineering
Biochemistry
General Chemistry
Biomedical Engineering

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title = "Step-emulsification in a microfluidic device",

abstract = "We present a comprehensive study of the step-emulsification process for high-throughput production of colloidal monodisperse droplets. The 'microfluidic step emulsifier' combines a shallow microchannel operating with two co-flowing immiscible fluids and an abrupt (step-like) opening to a deep and wide reservoir. Based on Hele-Shaw hydrodynamics, we determine the quasi-static shape of the fluid interface prior to transition to oscillatory step-emulsification at low capillary numbers. The theoretically derived transition threshold yields an excellent agreement with experimental data. A closed-form expression for the size of the droplets generated in the step-emulsification regime and derived using geometric arguments also shows a very good agreement with the experiment.",

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AU - Li, Z.

AU - Leshansky, A. M.

AU - Pismen, L. M.

AU - Tabeling, P.

PY - 2015/2/21

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N2 - We present a comprehensive study of the step-emulsification process for high-throughput production of colloidal monodisperse droplets. The 'microfluidic step emulsifier' combines a shallow microchannel operating with two co-flowing immiscible fluids and an abrupt (step-like) opening to a deep and wide reservoir. Based on Hele-Shaw hydrodynamics, we determine the quasi-static shape of the fluid interface prior to transition to oscillatory step-emulsification at low capillary numbers. The theoretically derived transition threshold yields an excellent agreement with experimental data. A closed-form expression for the size of the droplets generated in the step-emulsification regime and derived using geometric arguments also shows a very good agreement with the experiment.

AB - We present a comprehensive study of the step-emulsification process for high-throughput production of colloidal monodisperse droplets. The 'microfluidic step emulsifier' combines a shallow microchannel operating with two co-flowing immiscible fluids and an abrupt (step-like) opening to a deep and wide reservoir. Based on Hele-Shaw hydrodynamics, we determine the quasi-static shape of the fluid interface prior to transition to oscillatory step-emulsification at low capillary numbers. The theoretically derived transition threshold yields an excellent agreement with experimental data. A closed-form expression for the size of the droplets generated in the step-emulsification regime and derived using geometric arguments also shows a very good agreement with the experiment.

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DO - 10.1039/c4lc01289e

M3 - مقالة

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EP - 1031

JO - Lab on a Chip

JF - Lab on a Chip

IS - 4

ER -

Step-emulsification in a microfluidic device

Abstract

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