Slip slidin' away of mitosis with CRL2Zyg11

Michael Brandeis

doi:10.1083/jcb.201609086

Slip slidin' away of mitosis with CRL2Zyg11

Michael Brandeis

Department of Genetics

The Hebrew University of Jerusalem

Research output: Contribution to journal › Article › peer-review

Abstract

The spindle assembly checkpoint arrests mitotic cells by preventing degradation of cyclin B1 by the anaphasepromoting complex/cyclosome, but some cells evade this checkpoint and slip out of mitosis. Balachandran et al. (2016. J. Cell Biol. http ://dx .doi .org /10 .1083 /jcb .201601083) show that the E3 ligase CRL2^ZYG11 degrades cyclin B1, allowing mitotic slippage.

Original language	English
Pages (from-to)	143-145
Number of pages	3
Journal	Journal of Cell Biology
Volume	215
Issue number	2
DOIs	https://doi.org/10.1083/jcb.201609086
State	Published - 2016

All Science Journal Classification (ASJC) codes

Cell Biology

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10.1083/jcb.201609086

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title = "Slip slidin' away of mitosis with CRL2Zyg11",

abstract = "The spindle assembly checkpoint arrests mitotic cells by preventing degradation of cyclin B1 by the anaphasepromoting complex/cyclosome, but some cells evade this checkpoint and slip out of mitosis. Balachandran et al. (2016. J. Cell Biol. http ://dx .doi .org /10 .1083 /jcb .201601083) show that the E3 ligase CRL2ZYG11 degrades cyclin B1, allowing mitotic slippage.",

author = "Michael Brandeis",

note = "Publisher Copyright: {\textcopyright} 2016 Brandeis.",

year = "2016",

doi = "10.1083/jcb.201609086",

language = "الإنجليزيّة",

volume = "215",

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AU - Brandeis, Michael

PY - 2016

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N2 - The spindle assembly checkpoint arrests mitotic cells by preventing degradation of cyclin B1 by the anaphasepromoting complex/cyclosome, but some cells evade this checkpoint and slip out of mitosis. Balachandran et al. (2016. J. Cell Biol. http ://dx .doi .org /10 .1083 /jcb .201601083) show that the E3 ligase CRL2ZYG11 degrades cyclin B1, allowing mitotic slippage.

AB - The spindle assembly checkpoint arrests mitotic cells by preventing degradation of cyclin B1 by the anaphasepromoting complex/cyclosome, but some cells evade this checkpoint and slip out of mitosis. Balachandran et al. (2016. J. Cell Biol. http ://dx .doi .org /10 .1083 /jcb .201601083) show that the E3 ligase CRL2ZYG11 degrades cyclin B1, allowing mitotic slippage.

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U2 - 10.1083/jcb.201609086

DO - 10.1083/jcb.201609086

M3 - مقالة

C2 - 27810907

SN - 0021-9525

VL - 215

SP - 143

EP - 145

JO - Journal of Cell Biology

JF - Journal of Cell Biology

IS - 2

ER -

Slip slidin' away of mitosis with CRL2Zyg11

Abstract

All Science Journal Classification (ASJC) codes

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