Abstract
The spindle assembly checkpoint arrests mitotic cells by preventing degradation of cyclin B1 by the anaphasepromoting complex/cyclosome, but some cells evade this checkpoint and slip out of mitosis. Balachandran et al. (2016. J. Cell Biol. http ://dx .doi .org /10 .1083 /jcb .201601083) show that the E3 ligase CRL2ZYG11 degrades cyclin B1, allowing mitotic slippage.
| Original language | English |
|---|---|
| Pages (from-to) | 143-145 |
| Number of pages | 3 |
| Journal | Journal of Cell Biology |
| Volume | 215 |
| Issue number | 2 |
| DOIs | |
| State | Published - 2016 |
All Science Journal Classification (ASJC) codes
- Cell Biology