Single-stranded DNA detection by solvent-induced assemblies of a metallo-peptide-based complex

Priyadip Das, Meital Reches

Research output: Contribution to journalArticlepeer-review


DNA detection is highly important for the sensitive sensing of different pathogenic bacteria and viruses. The major challenge is to create a sensor that can selectively detect very small concentrations of DNA without the need for amplification or complicated equipment. Different technologies such as optical, electrochemical and microgravimetric approaches can detect DNA fragments. Here we show, for the first time, the use of self-assembled nanostructures generated by a metallo-peptide as an optical sensing platform for DNA detection. The system can selectively detect single stranded DNA fragments by fluorescence measurements as it can discriminate even one base mismatch and can perform in the presence of other interfering proteins. This system may be useful in lab-on-a-chip applications.

Original languageAmerican English
Pages (from-to)9527-9536
Number of pages10
Issue number18
StatePublished - 14 May 2016

All Science Journal Classification (ASJC) codes

  • General Materials Science


Dive into the research topics of 'Single-stranded DNA detection by solvent-induced assemblies of a metallo-peptide-based complex'. Together they form a unique fingerprint.

Cite this