Single-molecule DNA detection using a novel SP1 protein nanopore

Hai Yan Wang; Yang Li; Li Xia Qin; Arnon Heyman; Oded Shoseyov; Itamar Willner; Yi Tao Long; He Tian

doi:10.1039/c3cc38939a

Single-molecule DNA detection using a novel SP1 protein nanopore

Hai Yan Wang, Yang Li, Li Xia Qin, Arnon Heyman, Oded Shoseyov, Itamar Willner, Yi Tao Long, He Tian

The Hebrew University of Jerusalem

Research output: Contribution to journal › Article › peer-review

Abstract

SP1 protein as a new type of biological nanopore is described and is utilized to distinguish single-stranded DNA at the single-molecule level. Using the SP1 nanopore to investigate single molecule detection broadens the existing research areas of pore-forming biomaterials from unsymmetrical biological nanopores to symmetrical biological nanopores. This novel nanopore could provide a good candidate for single-molecule detection and characterization of biomaterial applications.

Original language	English
Pages (from-to)	1741-1743
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	17
DOIs	https://doi.org/10.1039/c3cc38939a
State	Published - 31 Jan 2013

All Science Journal Classification (ASJC) codes

Electronic, Optical and Magnetic Materials
Catalysis
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c3cc38939a

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title = "Single-molecule DNA detection using a novel SP1 protein nanopore",

abstract = "SP1 protein as a new type of biological nanopore is described and is utilized to distinguish single-stranded DNA at the single-molecule level. Using the SP1 nanopore to investigate single molecule detection broadens the existing research areas of pore-forming biomaterials from unsymmetrical biological nanopores to symmetrical biological nanopores. This novel nanopore could provide a good candidate for single-molecule detection and characterization of biomaterial applications.",

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AU - Wang, Hai Yan

AU - Li, Yang

AU - Qin, Li Xia

AU - Heyman, Arnon

AU - Shoseyov, Oded

AU - Willner, Itamar

AU - Long, Yi Tao

AU - Tian, He

PY - 2013/1/31

Y1 - 2013/1/31

N2 - SP1 protein as a new type of biological nanopore is described and is utilized to distinguish single-stranded DNA at the single-molecule level. Using the SP1 nanopore to investigate single molecule detection broadens the existing research areas of pore-forming biomaterials from unsymmetrical biological nanopores to symmetrical biological nanopores. This novel nanopore could provide a good candidate for single-molecule detection and characterization of biomaterial applications.

AB - SP1 protein as a new type of biological nanopore is described and is utilized to distinguish single-stranded DNA at the single-molecule level. Using the SP1 nanopore to investigate single molecule detection broadens the existing research areas of pore-forming biomaterials from unsymmetrical biological nanopores to symmetrical biological nanopores. This novel nanopore could provide a good candidate for single-molecule detection and characterization of biomaterial applications.

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U2 - 10.1039/c3cc38939a

DO - 10.1039/c3cc38939a

M3 - مقالة

C2 - 23340583

SN - 1359-7345

VL - 49

SP - 1741

EP - 1743

JO - Chemical Communications

JF - Chemical Communications

IS - 17

ER -

Single-molecule DNA detection using a novel SP1 protein nanopore

Abstract

All Science Journal Classification (ASJC) codes

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