Abstract
Traditionally, gene expression measurements were performed on "bulk" samples containing populations of thousands of cells. Recent advances in genomic technology have made it possible to measure gene expression in hundreds of individual cells at a time. As a result, cellular properties that were previously masked in "bulk" measurements can now be observed directly. In this review we will survey emerging technologies for single cell transcriptomics, and describe how they are used to study complex disease such as cancer, as well as other biological phenomena such as tissue regeneration, embryonic development, and immune response.
| Original language | English |
|---|---|
| Article number | 53 |
| Journal | Frontiers in Oncology |
| Volume | 5 |
| Issue number | FEB |
| DOIs | |
| State | Published - 2015 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- FISH
- Gene expression
- RNA sequencing
- Single cell
- qPCR
All Science Journal Classification (ASJC) codes
- Oncology
- Cancer Research
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