Single cell transcriptomics: Methods and applications

Itamar Kanter, Tomer Kalisky

Research output: Contribution to journalReview articlepeer-review


Traditionally, gene expression measurements were performed on "bulk" samples containing populations of thousands of cells. Recent advances in genomic technology have made it possible to measure gene expression in hundreds of individual cells at a time. As a result, cellular properties that were previously masked in "bulk" measurements can now be observed directly. In this review we will survey emerging technologies for single cell transcriptomics, and describe how they are used to study complex disease such as cancer, as well as other biological phenomena such as tissue regeneration, embryonic development, and immune response.

Original languageEnglish
Article number53
JournalFrontiers in Oncology
Issue numberFEB
StatePublished - 2015


  • FISH
  • Gene expression
  • RNA sequencing
  • Single cell
  • qPCR

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research


Dive into the research topics of 'Single cell transcriptomics: Methods and applications'. Together they form a unique fingerprint.

Cite this