@inbook{fb3cbc944068411199ce10dbdbf7221a,
title = "Single-Cell Resolution Optogenetics Via Expression of Soma-Targeted Rhodopsins",
abstract = "Optogenetics allows control of neural activity in genetically targeted neuron populations by light. Optogenetic control of individual neurons in neural circuits would enable powerful, causal investigations of neural connectivity and function at single-cell level and provide insights into how neural circuits operate. Such single-cell resolution optogenetics in neuron populations requires precise sculpting of light and subcellular targeting of optogenetic molecules. Here we describe a group of methods for single-cell resolution optogenetics in neuron cultures, in mouse brain slices, and in mouse cortex in-vivo, via patterned light and soma-targeted optogenetic molecules.",
keywords = "Cell-body-targeted opsins, Computer-generated holography, Functional connectivity, Single-cell control, Single-cell optogenetics, Somatic optogenetics, Synaptic transmission, Two-photon stimulation",
author = "Changyang Linghu and Chen, \{I. Wen\} and Dimitrii Tanese and Valeria Zampini and Shemesh, \{Or A.\}",
note = "Publisher Copyright: {\textcopyright} 2022, The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.",
year = "2022",
doi = "10.1007/978-1-0716-2329-9\_11",
language = "الإنجليزيّة",
series = "Methods in Molecular Biology",
pages = "229--257",
booktitle = "Methods in Molecular Biology",
}