Silicon photonics ultrahigh-resolution in vivo optoacoustic tomography

Yoav Hazan, Ahiad Levi, Michael Nagli, Amir Rosenthal

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

A new ultrasound-detection technology is developed for ultrahigh-resolution optoacoustic tomography and is experimentally demonstrated with bandwidths exceeding 200 MHz and lateral resolutions beyond 20 µm. Our technology is based on an optical resonator fabricated in a silicon-photonics platform, which is coated by a sensitivity-enhancing polymer, which also eliminates the parasitic effect of surface acoustic waves. Further improvement in sensitivity is achieved by a low-noise interferometric setup, which eliminates the effect of laser frequency noise on the measurement. In vivo optoacoustic tomography is performed on a mouse ear, revealing its vasculature at detail that has been previously reserved to optoacoustic microscopy.

Original languageEnglish
Title of host publicationOpto-Acoustic Methods and Applications in Biophotonics VI
EditorsChulhong Kim, Jan Laufer, Vasilis Ntziachristos, Roger J. Zemp
ISBN (Electronic)9781510664715
DOIs
StatePublished - 2023
EventOpto-Acoustic Methods and Applications in Biophotonics VI 2023 - Munich, Germany
Duration: 25 Jun 202326 Jun 2023

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume12631

Conference

ConferenceOpto-Acoustic Methods and Applications in Biophotonics VI 2023
Country/TerritoryGermany
CityMunich
Period25/06/2326/06/23

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Applied Mathematics
  • Electrical and Electronic Engineering
  • Computer Science Applications

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