TY - JOUR
T1 - Shift-driven modulations of spin-echo signals
AU - Smith, Pieter E.S.
AU - Bensky, Guy
AU - Álvarez, Gonzalo A.
AU - Kurizki, Gershon
AU - Frydman, Lucio
N1 - Israel Science Foundation (ISF) [447/2009, 1404/08]; European Union through ERC [246754]; FET; Helen and Kimmel Award for Innovative Investigation; Fulbright Foundation; Humboldt Foundation; Humboldt-Meitner AwardWe are grateful to Prof. Dieter Suter (Dortmund) for encouraging discussions. This research was supported by the Israel Science Foundation (ISF 447/2009 and 1404/08), the European Union through ERC Advanced Grant 246754 and the FET Open MIDAS project, a Helen and Kimmel Award for Innovative Investigation, and the generosity of the Perlman Family Foundation. P.E.S.S. is grateful to the Fulbright Foundation for a postdoctoral fellowship; G.A.A. thanks the Humboldt Foundation for financial support; G.K. acknowledges the support of a Humboldt-Meitner Award.
PY - 2012/4/17
Y1 - 2012/4/17
N2 - Since the pioneering works of Carr-Purcell and Meiboom-Gill [Carr HY, Purcell EM (1954) Phys Rev 94:630; Meiboom S, Gill D (1985) Rev Sci Instrum 29:688], trains of π-pulses have featured amongst the main tools of quantum control. Echo trains find widespread use in nuclear magnetic resonance spectroscopy (NMR) and imaging (MRI), thanks to their ability to free the evolution of a spin-1/2 from several sources of decoherence. Spin echoes have also been researched in dynamic decoupling scenarios, for prolonging the lifetimes of quantum states or coherences. Inspired by this search we introduce a family of spin-echo sequences, which can still detect site-specific interactions like the chemical shift. This is achieved thanks to the presence of weak environmental fluctuations of common occurrence in high-field NMR - such as homonuclear spin-spin couplings or chemical/biochemical exchanges. Both intuitive and rigorous derivations of the resulting "selective dynamical recoupling" sequences are provided. Applications of these novel experiments are given for a variety of NMR scenarios including determinations of shift effects under inhomogeneities overwhelming individual chemical identities, and model-free characterizations of chemically exchanging partners.
AB - Since the pioneering works of Carr-Purcell and Meiboom-Gill [Carr HY, Purcell EM (1954) Phys Rev 94:630; Meiboom S, Gill D (1985) Rev Sci Instrum 29:688], trains of π-pulses have featured amongst the main tools of quantum control. Echo trains find widespread use in nuclear magnetic resonance spectroscopy (NMR) and imaging (MRI), thanks to their ability to free the evolution of a spin-1/2 from several sources of decoherence. Spin echoes have also been researched in dynamic decoupling scenarios, for prolonging the lifetimes of quantum states or coherences. Inspired by this search we introduce a family of spin-echo sequences, which can still detect site-specific interactions like the chemical shift. This is achieved thanks to the presence of weak environmental fluctuations of common occurrence in high-field NMR - such as homonuclear spin-spin couplings or chemical/biochemical exchanges. Both intuitive and rigorous derivations of the resulting "selective dynamical recoupling" sequences are provided. Applications of these novel experiments are given for a variety of NMR scenarios including determinations of shift effects under inhomogeneities overwhelming individual chemical identities, and model-free characterizations of chemically exchanging partners.
UR - http://www.scopus.com/inward/record.url?scp=84859956531&partnerID=8YFLogxK
U2 - 10.1073/pnas.1120704109
DO - 10.1073/pnas.1120704109
M3 - مقالة
SN - 0027-8424
VL - 109
SP - 5958
EP - 5961
JO - Proceedings of the National Academy of Sciences of the United States of America
JF - Proceedings of the National Academy of Sciences of the United States of America
IS - 16
ER -