Seroprevalence and risk factors for exposure to equine coronavirus in apparently healthy horses in israel

Gili Schvartz, Sharon Tirosh-Levy, Samantha Barnum, Dan David, Asaf Sol, Nicola Pusterla, Amir Steinman

Research output: Contribution to journalArticlepeer-review


Equine coronavirus (ECoV) infection is the cause of an emerging enteric disease of adult horses. Outbreaks have been reported in the USA, EU and Japan, as well as sporadic cases in the UK and Saudi Arabia. Infection of ECoV in horses in Israel has never been reported, and the risk of exposure is unknown. Importation and exportation of horses from and into Israel may have increased the exposure of horses in Israel to ECoV. While the disease is mostly self-limiting, with or without supportive treatment, severe complications may occur in some animals, and healthy carriers may pose a risk of infection to other horses. This study was set to evaluate the risk of exposure to ECoV of horses in Israel by using a previously validated, S1-based enzyme-linked immunosorbent assay (ELISA). A total of 41 out of 333 horses (12.3%) were seropositive. Exposure to ECoV was detected in 17 of 29 farms (58.6%) and the seroprevalence varied between 0 and 37.5% amongst farms. The only factor found to be significantly associated with ECoV exposure in the multivariable model was the geographical area (p < 0.001). ECoV should be included in the differential diagnosis list of pathogens in cases of adult horses with anorexia, lethargy, fever and gastrointestinal signs in Israel.

Original languageAmerican English
Article number894
Pages (from-to)1-7
Number of pages7
Issue number3
StatePublished - Mar 2021


  • ECoV
  • Enteric disease
  • Equine coronavirus
  • Horse
  • Seroprevalence

All Science Journal Classification (ASJC) codes

  • Animal Science and Zoology
  • General Veterinary


Dive into the research topics of 'Seroprevalence and risk factors for exposure to equine coronavirus in apparently healthy horses in israel'. Together they form a unique fingerprint.

Cite this