Self-assembling peptides and proteins into dynamic, functional, adhesive, and self-healing structures

K Inostroza Brito, E Collin, O Siton-Mendelson, K Smith, A Mongue-Marcet, D Ferreira, R Perez, M Alonso, J Rodriguez-Cabello, R Reis, Ronit Bitton

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Manipulation, spatio-temporal control, and hierarchical order of proteins are major goals for the next generation of functional biomaterials. However, the capacity to accurately control self-assembly of these building-blocks across scales with significant spatial and temporal control is still limited. Here we present a protein/peptide self-assembling system that exhibits hierarchical architecture, controlled assembly capabilities, adhesion to surfaces, self-healing, and the capacity to undergo morphogenesis into complex geometries with high spatio-temporal control. We demonstrate the potential of the system for fabricating bioactive and biomimetic scaffolds for tissue engineering.
Original languageEnglish
Title of host publicationFront. Bioeng. Biotechnol. Conference Abstract: 10th World Biomaterials Congress. doi: 10.3389/conf. FBIOE
Volume2907
StatePublished - 2016

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