@article{98ff402e0423456eb586d8b4113c76b7,
title = "SARS-CoV-2 (COVID-19) by the numbers",
abstract = "The current SARS-CoV-2 pandemic is a harsh reminder of the fact that, whether in a single human host or a wave of infection across continents, viral dynamics is often a story about the numbers. In this snapshot, our aim is to provide a one-stop, curated graphical source for the key numbers that help us understand the virus driving our current global crisis. The discussion is framed around two broad themes: 1) the biology of the virus itself and 2) the characteristics of the infection of a single human host. Our one-page summary provides the key numbers pertaining to SARS-CoV-2, based mostly on peer-reviewed literature. The numbers reported in summary format are substantiated by the annotated references below. Readers are urged to remember that much uncertainty remains and knowledge of this pandemic and the virus driving it is rapidly evolving. In the paragraphs below we provide “back of the envelope” calculations that exemplify the insights that can be gained from knowing some key numbers and using quantitative logic. These calculations serve to improve our intuition through sanity checks, but do not replace detailed epidemiological analysis.",
author = "Bar-On, \{Yinon M.\} and Avi Flamholz and Rob Phillips and Ron Milo",
note = "We thank the following individuals for productive feedback on this manuscript: Uri Alon, Niv Antonovsky, David Baltimore, Rachel Banks, Arren Bar Even, Naama Barkai, Molly Bassette, Menalu Berihoon, Biana Bernshtein, Pamela Bjorkman, Cecilia Blikstad, Julia Borden, Bill Burkholder, Griffin Chure, Lillian Cohn, Bernadeta Dadonaite, Emmie De wit, Ron Diskin, Ana Duarte, Tal Einav, Avigdor Eldar, Elizabeth Fischer, William Gelbart, Alon Gildoni, Britt Glausinger, Shmuel Gleizer, Dani Gluck, Soichi Hirokawa, Greg Huber, Christina Hueschen, Amit Huppert, Shalev Itzkovitz, Martin Jonikas, Leeat Keren, Gilmor Keshet, Marc Kirschner, Roy Kishony, Amy Kistler, Liad Levi, Sergei Maslov, Adi Millman, Amir Milo, Elad Noor, Gal Ofir, Alan Perelson, Steve Quake, Itai Raveh, Andrew Rennekamp, Tom Roeschinger, Daniel Rokhsar, Alex Rubinsteyn, Gabriel Salmon, Maya Schuldiner, Eran Segal, Ron Sender, Alex Sigal, Maya Shamir, Arik Shams, Mike Springer, Adi Stern, Noam Stern-Ginossar, Lubert Stryer, Dan Tawfik, Boris Veytsman, Aryeh Wides, Tali Wiesel, Anat Yarden, Yossi Yovel, Dudi Zeevi, Mushon Zer Aviv, and Alexander Zlokapa. Author contributions - Yinon M Bar-On, Conceptualization, Resources, Data curation, Formal analysis, Validation, Investigation, Methodology, Writing - original draft, Writing - review and editing; Avi Flamholz, Resources, Data curation, Formal analysis, Validation, Investigation, Methodology, Writing - original draft, Writing - review and editing; Rob Phillips, Conceptualization, Resources, Data curation, Formal analysis, Supervision, Funding acquisition, Validation, Investigation, Methodology, Writing - original draft, Writing - review and editing; Ron Milo, Conceptualization, Resources, Data curation, Formal analysis, Supervision, Funding acquisition, Validation, Investigation, Methodology, Writing - original draft, Project administration, Writing - review and editing Funding: National Institutes of Health (1R35 GM118043-01 (Maximizing Investigators Research Award)) Weizmann Institute of Science (Charles and Louise Gartner professorial chair) The Azrieli Foundation (Azrieli Fellow).",
year = "2020",
month = mar,
day = "31",
doi = "10.7554/eLife.57309",
language = "الإنجليزيّة",
volume = "9",
journal = "eLife",
issn = "2050-084X",
publisher = "eLife Sciences Publications Ltd",
}