We give round-optimal black-box constructions of two-party and multiparty protocols in the common random/reference string (CRS) model, with security against malicious adversaries, based on any two-round oblivious transfer (OT) protocol in the same model. Specifically, we obtain two types of results. 1.Two-party protocol. We give a (two-round) two-sided NISC protocol that makes black-box use of two-round (malicious-secure) OT in the CRS model. In contrast to the standard setting of non-interactive secure computation (NISC), two-sided NISC allows communication from both parties in each round and delivers the output to both parties at the end of the protocol. Prior black-box constructions of two-sided NISC relied on idealized setup assumptions such as OT correlations, or were proven secure in the random oracle model.2.Multiparty protocol. We give a three-round secure multiparty computation protocol for an arbitrary number of parties making black-box use of a two-round OT in the CRS model. The round optimality of this construction follows from a black-box impossibility proof of Applebaum et al. (ITCS 2020). Prior constructions either required the use of random oracles, or were based on two-round malicious-secure OT protocols that satisfied additional security properties.