Role of the endocannabinoid system in hepatic lipogenesis

Joseph Tam

doi:10.1007/978-3-319-25065-6_6

Role of the endocannabinoid system in hepatic lipogenesis

Joseph Tam

School of Pharmacy

The Hebrew University of Jerusalem

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Endocannabinoids are endogenous lipid mediators recognized by the cannabinoid-1 and 2 (CB₁ and CB₂, respectively) receptors that mediate the effects of marijuana. The endocannabinoid system, consisting of endocannabinoids (eCBs), their receptors, and the enzymes involved in their biosynthesis and degradation, is present in many tissues including the liver. The present chapter reviews accumulating evidence that the eCB system is involved in the regulation of de novo hepatic lipogenesis.

Original language	English
Title of host publication	Hepatic De Novo Lipogenesis and Regulation of Metabolism
Pages	131-142
Number of pages	12
ISBN (Electronic)	9783319250656
DOIs	https://doi.org/10.1007/978-3-319-25065-6_6
State	Published - 1 Jan 2015

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

CB receptor
Diet-induced obesity
Endocannabinoids
Fatty liver
Hepatic lipogenesis
Monounsaturated fatty acids

ASJC Scopus subject areas

General Biochemistry,Genetics and Molecular Biology
General Medicine

Access to Document

10.1007/978-3-319-25065-6_6

Cite this

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abstract = "Endocannabinoids are endogenous lipid mediators recognized by the cannabinoid-1 and 2 (CB1 and CB2, respectively) receptors that mediate the effects of marijuana. The endocannabinoid system, consisting of endocannabinoids (eCBs), their receptors, and the enzymes involved in their biosynthesis and degradation, is present in many tissues including the liver. The present chapter reviews accumulating evidence that the eCB system is involved in the regulation of de novo hepatic lipogenesis.",

keywords = "CB receptor, Diet-induced obesity, Endocannabinoids, Fatty liver, Hepatic lipogenesis, Monounsaturated fatty acids",

author = "Joseph Tam",

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AB - Endocannabinoids are endogenous lipid mediators recognized by the cannabinoid-1 and 2 (CB1 and CB2, respectively) receptors that mediate the effects of marijuana. The endocannabinoid system, consisting of endocannabinoids (eCBs), their receptors, and the enzymes involved in their biosynthesis and degradation, is present in many tissues including the liver. The present chapter reviews accumulating evidence that the eCB system is involved in the regulation of de novo hepatic lipogenesis.

KW - CB receptor

KW - Diet-induced obesity

KW - Endocannabinoids

KW - Fatty liver

KW - Hepatic lipogenesis

KW - Monounsaturated fatty acids

UR - https://www.scopus.com/pages/publications/85008949758

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BT - Hepatic De Novo Lipogenesis and Regulation of Metabolism

ER -

Role of the endocannabinoid system in hepatic lipogenesis

Abstract

UN SDGs

Keywords

ASJC Scopus subject areas

Access to Document

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