Robustness of synthetic circadian clocks to multiple environmental changes

Lilia Gurevich; Rivka Cohen-Luria; Nathaniel Wagner; Gonen Ashkenasy

doi:10.1039/c5cc00098j

Robustness of synthetic circadian clocks to multiple environmental changes

Lilia Gurevich
, Rivka Cohen-Luria
, Nathaniel Wagner
, Gonen Ashkenasy

Department of Chemistry

Ben-Gurion University of the Negev

Research output: Contribution to journal › Article › peer-review

Abstract

A molecular network that mimics circadian clocks from cyanobacteria is constructed in silico. Simulating its oscillatory behaviour under variable conditions reveals its robustness relative to networks of alternative topologies. The principles for synthetic chemical circadian networks to work properly are consequently highlighted.

Original language	American English
Pages (from-to)	5672-5675
Number of pages	4
Journal	Chemical Communications
Volume	51
Issue number	26
DOIs	https://doi.org/10.1039/c5cc00098j
State	Published - 4 Apr 2015

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c5cc00098j

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title = "Robustness of synthetic circadian clocks to multiple environmental changes",

abstract = "A molecular network that mimics circadian clocks from cyanobacteria is constructed in silico. Simulating its oscillatory behaviour under variable conditions reveals its robustness relative to networks of alternative topologies. The principles for synthetic chemical circadian networks to work properly are consequently highlighted.",

author = "Lilia Gurevich and Rivka Cohen-Luria and Nathaniel Wagner and Gonen Ashkenasy",

note = "Publisher Copyright: {\textcopyright} 2015 The Royal Society of Chemistry.",

year = "2015",

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doi = "10.1039/c5cc00098j",

language = "American English",

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T1 - Robustness of synthetic circadian clocks to multiple environmental changes

AU - Gurevich, Lilia

AU - Cohen-Luria, Rivka

AU - Wagner, Nathaniel

AU - Ashkenasy, Gonen

PY - 2015/4/4

Y1 - 2015/4/4

N2 - A molecular network that mimics circadian clocks from cyanobacteria is constructed in silico. Simulating its oscillatory behaviour under variable conditions reveals its robustness relative to networks of alternative topologies. The principles for synthetic chemical circadian networks to work properly are consequently highlighted.

AB - A molecular network that mimics circadian clocks from cyanobacteria is constructed in silico. Simulating its oscillatory behaviour under variable conditions reveals its robustness relative to networks of alternative topologies. The principles for synthetic chemical circadian networks to work properly are consequently highlighted.

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U2 - 10.1039/c5cc00098j

DO - 10.1039/c5cc00098j

M3 - Article

SN - 1359-7345

VL - 51

SP - 5672

EP - 5675

JO - Chemical Communications

JF - Chemical Communications

IS - 26

ER -

Robustness of synthetic circadian clocks to multiple environmental changes

Abstract

ASJC Scopus subject areas

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