Risk factors and correlates of protection against XBB SARS-CoV-2 infection among health care workers

Michal Canetti; Noam Barda; Yaniv Lustig; Yael Weiss-Ottolenghi; Victoria Indenbaum; Yovel Peretz; Neta Zuckerman; Keren Asraf; Sharon Amit; Yitshak Kreiss; Gili Regev-Yochay

doi:10.1016/j.vaccine.2024.126308

Risk factors and correlates of protection against XBB SARS-CoV-2 infection among health care workers

Michal Canetti, Noam Barda, Yaniv Lustig, Yael Weiss-Ottolenghi, Victoria Indenbaum, Yovel Peretz, Neta Zuckerman, Keren Asraf, Sharon Amit, Yitshak Kreiss, Gili Regev-Yochay

Tel Aviv University, Ben-Gurion University of the Negev

Research output: Contribution to journal › Article › peer-review

Abstract

Correlates of protection for recent emerging SARS-CoV-2 variants have not been determined. In this test-negative case-control study, we report lower odds of infection with XBB variants among those boosted during the last six months. Additionally, we demonstrate that XBB-specific neutralizing antibodies are independent correlates of protection.

Original language	English
Article number	126308
Journal	Vaccine
Volume	42
Issue number	26
DOIs	https://doi.org/10.1016/j.vaccine.2024.126308
State	Published - 2 Dec 2024

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

COVID-19
Correlates of protection
Omicron
XBB

All Science Journal Classification (ASJC) codes

Molecular Medicine
General Immunology and Microbiology
General Veterinary
Public Health, Environmental and Occupational Health
Infectious Diseases

Access to Document

10.1016/j.vaccine.2024.126308

Cite this

@article{654a053f33374d9580c8e8474a6db384,

title = "Risk factors and correlates of protection against XBB SARS-CoV-2 infection among health care workers",

abstract = "Correlates of protection for recent emerging SARS-CoV-2 variants have not been determined. In this test-negative case-control study, we report lower odds of infection with XBB variants among those boosted during the last six months. Additionally, we demonstrate that XBB-specific neutralizing antibodies are independent correlates of protection.",

keywords = "COVID-19, Correlates of protection, Omicron, XBB",

author = "Michal Canetti and Noam Barda and Yaniv Lustig and Yael Weiss-Ottolenghi and Victoria Indenbaum and Yovel Peretz and Neta Zuckerman and Keren Asraf and Sharon Amit and Yitshak Kreiss and Gili Regev-Yochay",

note = "Publisher Copyright: {\textcopyright} 2024",

year = "2024",

month = dec,

day = "2",

doi = "10.1016/j.vaccine.2024.126308",

language = "الإنجليزيّة",

volume = "42",

journal = "Vaccine",

issn = "0264-410X",

publisher = "Elsevier Ltd.",

number = "26",

}

TY - JOUR

T1 - Risk factors and correlates of protection against XBB SARS-CoV-2 infection among health care workers

AU - Canetti, Michal

AU - Barda, Noam

AU - Lustig, Yaniv

AU - Weiss-Ottolenghi, Yael

AU - Indenbaum, Victoria

AU - Peretz, Yovel

AU - Zuckerman, Neta

AU - Asraf, Keren

AU - Amit, Sharon

AU - Kreiss, Yitshak

AU - Regev-Yochay, Gili

PY - 2024/12/2

Y1 - 2024/12/2

N2 - Correlates of protection for recent emerging SARS-CoV-2 variants have not been determined. In this test-negative case-control study, we report lower odds of infection with XBB variants among those boosted during the last six months. Additionally, we demonstrate that XBB-specific neutralizing antibodies are independent correlates of protection.

AB - Correlates of protection for recent emerging SARS-CoV-2 variants have not been determined. In this test-negative case-control study, we report lower odds of infection with XBB variants among those boosted during the last six months. Additionally, we demonstrate that XBB-specific neutralizing antibodies are independent correlates of protection.

KW - COVID-19

KW - Correlates of protection

KW - Omicron

KW - XBB

UR - http://www.scopus.com/inward/record.url?scp=85203408258&partnerID=8YFLogxK

U2 - 10.1016/j.vaccine.2024.126308

DO - 10.1016/j.vaccine.2024.126308

M3 - مقالة

C2 - 39255646

SN - 0264-410X

VL - 42

JO - Vaccine

JF - Vaccine

IS - 26

M1 - 126308

ER -

Risk factors and correlates of protection against XBB SARS-CoV-2 infection among health care workers

Abstract

UN SDGs

Keywords

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this