Rescue of the First Mitochondrial Membrane Carrier, the mPiC, by TAT-Mediated Protein Replacement Treatment

Keyphrases

• Fusion Protein 100%
• Replacement Treatment 100%
• Mitochondria-associated Membranes 100%
• Membrane Carrier 100%
• Protein Replacement Therapy 100%
• Mitochondria 40%
• ATP Production 40%
• Mitochondrial Matrix 40%
• SLC25A3 40%
• Treatment Strategy 20%
• Cell Growth 20%
• Mitochondrial Function 20%
• Autosomal Recessive 20%
• Early Treatment 20%
• Novel Therapeutics 20%
• Ca2+ 20%
• Knockdown 20%
• N-terminus 20%
• First Year of Life 20%
• Nuclear Genes 20%
• Bioenergetics 20%
• Transmembrane 20%
• Biological Membranes 20%
• TAT Peptide 20%
• Holoenzyme 20%
• Inorganic Phosphate 20%
• Phosphorylation Reaction 20%
• Oxygen Consumption Rate 20%
• Mitochondrial Ca2+ Uptake 20%
• Ca2+ Buffering 20%
• Fusion Systems 20%
• Mitochondrial Targeting Sequence 20%
• Cellular Location 20%
• Cellular Delivery 20%
• Mitochondrial Phosphate Carrier 20%

Biochemistry, Genetics and Molecular Biology

• Chimeric Protein 100%
• Outer Mitochondrial Membrane 100%
• Mitochondrial Membrane 100%
• Mitochondrion 40%
• Mitochondrial Matrix 40%
• N-Terminus 20%
• Secretion (Process) 20%
• Autosomal Recessive Disorder 20%
• Cell Growth 20%
• Adenosine Triphosphate 20%
• Oxygen Consumption 20%
• Nuclear Gene 20%
• Biomembrane 20%
• Bioenergetics 20%
• Mitochondrial Targeting Signal 20%