@inbook{1a9f7a8ce26948f78bf9d0ad6d41fb3f,
title = "Protocol for high-content screening for the impact of overexpressed MicroRNAs on primary motor neurons",
abstract = "In this chapter we provide a protocol for the design and usage of automated, high-content microscopy screening that enables the investigation of microRNA (miRNA) impact on primary motor neuron. High-content screening (HCS) platforms facilitate superior precision in research and are scalable to study in parallel multiple genetic, molecular, or cellular conditions. miRNAs are critical for neuronal function and for brain integrity and are considered attractive candidate targets for therapy in many neuropathologies. Therefore, HCS platforms provide a novel paradigm for exploring the impact of miRNA expression, applicable for functional pathways discovery in an academic setting, or towards development of therapeutics in the pharma industry.",
author = "Tal Yardeni and Eran Hornstein",
note = "Publisher Copyright: {\textcopyright} 2016, Springer Science+Business Media New York.",
year = "2016",
month = nov,
day = "15",
doi = "https://doi.org/10.1007/7657_2016_1",
language = "الإنجليزيّة",
series = "Neuromethods",
publisher = "Humana Press",
pages = "11--19",
editor = "{Jeong Kye}, Min",
booktitle = "MicroRNA Technologies",
address = "الولايات المتّحدة",
}