Progress in Treatment and Diagnostics of Infectious Disease with Polymers

Sukanya Patra, Divya Pareek, Prem Shankar Gupta, Kirti Wasnik, Gurmeet Singh, Desh Deepak Yadav, Yitzhak Mastai, Pradip Paik

Research output: Contribution to journalReview articlepeer-review


In this era of advanced technology and innovation, infectious diseases still cause significant morbidity and mortality, which need to be addressed. Despite overwhelming success in the development of vaccines, transmittable diseases such as tuberculosis and AIDS remain unprotected, and the treatment is challenging due to frequent mutations of the pathogens. Formulations of new or existing drugs with polymeric materials have been explored as a promising new approach. Variations in shape, size, surface charge, internal morphology, and functionalization position polymer particles as a revolutionary material in healthcare. Here, an overview is provided of major diseases along with statistics on infection and death rates, focusing on polymer-based treatments and modes of action. Key issues are discussed in this review pertaining to current challenges and future perspectives.

Original languageEnglish
Pages (from-to)287-316
Number of pages30
JournalACS Infectious Diseases
Issue number2
Early online date18 Jan 2024
StatePublished - 9 Feb 2024


  • Diagnostics
  • Infectious diseases
  • Polymer nanoparticles
  • Therapeutics
  • Vaccination

All Science Journal Classification (ASJC) codes

  • Infectious Diseases


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